Application site pruritus: Which Medications Cause It? (16,233 Reports Across 141 Drugs)
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Application site pruritus has been reported as an adverse event with 141 different drugs in the FDA's FAERS database, with 16,233 total reports. 39 of these reports resulted in death.The drugs most commonly associated with Application site pruritus are MINOXIDIL, NICOTINE, and BUPRENORPHINE.
16,233
Total Reports
141
Drugs Involved
39
Deaths
339
Hospitalizations
54.7 yrs
Average Patient Age
65.4% / 34.6%
Female / Male
Which Drugs Cause Application site pruritus Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| MINOXIDIL | 3,727 | 6.1% | 0 | 6 | 0 |
| NICOTINE | 2,074 | 6.4% | 0 | 2 | 1 |
| BUPRENORPHINE | 1,687 | 2.1% | 1 | 24 | 1 |
| ESTRADIOL | 1,181 | 3.8% | 0 | 0 | 0 |
| SUMATRIPTAN | 675 | 3.9% | 0 | 2 | 0 |
| FENTANYL | 501 | 0.5% | 1 | 6 | 1 |
| ESTRADIOL\NORETHINDRONE | 463 | 10.8% | 0 | 0 | 2 |
| CLONIDINE | 335 | 2.7% | 0 | 3 | 0 |
| ROTIGOTINE | 334 | 4.3% | 8 | 36 | 3 |
| INGENOL MEBUTATE | 291 | 9.6% | 0 | 2 | 0 |
| OXYBUTYNIN | 289 | 3.7% | 0 | 1 | 0 |
| METHYLPHENIDATE | 260 | 0.8% | 0 | 2 | 0 |
| DICLOFENAC | 259 | 0.3% | 0 | 0 | 0 |
| TESTOSTERONE | 253 | 0.9% | 0 | 3 | 0 |
| OXYTROL FOR WOMEN | 245 | 8.4% | 0 | 0 | 0 |
| MECHLORETHAMINE | 227 | 8.8% | 0 | 10 | 0 |
| ETHINYL ESTRADIOL\NORELGESTROMIN | 215 | 3.2% | 0 | 0 | 1 |
| RIVASTIGMINE | 210 | 2.3% | 4 | 37 | 3 |
| CRISABOROLE | 139 | 1.8% | 1 | 0 | 0 |
| DAYTRANA | 122 | 8.4% | 0 | 0 | 0 |