Application site reaction: Which Medications Cause It? (3,471 Reports Across 83 Drugs)
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Application site reaction has been reported as an adverse event with 83 different drugs in the FDA's FAERS database, with 3,471 total reports. 9 of these reports resulted in death.The drugs most commonly associated with Application site reaction are NICOTINE, BUPRENORPHINE, and FENTANYL.
3,471
Total Reports
83
Drugs Involved
9
Deaths
135
Hospitalizations
54.3 yrs
Average Patient Age
70.2% / 29.8%
Female / Male
Which Drugs Cause Application site reaction Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| NICOTINE | 640 | 2.0% | 0 | 6 | 0 |
| BUPRENORPHINE | 503 | 0.6% | 0 | 3 | 0 |
| FENTANYL | 223 | 0.2% | 0 | 9 | 1 |
| CHLORHEXIDINE\ISOPROPYL ALCOHOL | 216 | 3.8% | 1 | 4 | 0 |
| MINOXIDIL | 179 | 0.3% | 0 | 3 | 0 |
| INGENOL MEBUTATE | 160 | 5.3% | 0 | 5 | 1 |
| ESTRADIOL | 157 | 0.5% | 0 | 1 | 0 |
| ROTIGOTINE | 110 | 1.4% | 1 | 8 | 0 |
| SUMATRIPTAN | 86 | 0.5% | 0 | 0 | 0 |
| DICLOFENAC | 72 | 0.1% | 0 | 4 | 0 |
| ESTRADIOL\NORETHINDRONE | 59 | 1.4% | 0 | 0 | 0 |
| ETHINYL ESTRADIOL\NORELGESTROMIN | 48 | 0.7% | 0 | 0 | 0 |
| DOCOSANOL | 47 | 0.6% | 0 | 0 | 0 |
| TESTOSTERONE | 46 | 0.2% | 0 | 0 | 1 |
| RIVASTIGMINE | 44 | 0.5% | 2 | 8 | 0 |
| SCOPOLAMINE | 38 | 1.4% | 0 | 3 | 0 |
| PEGFILGRASTIM | 37 | 0.1% | 0 | 0 | 0 |
| CLONIDINE | 31 | 0.3% | 0 | 1 | 0 |
| LIDOCAINE | 29 | 0.1% | 0 | 2 | 0 |
| MECHLORETHAMINE | 28 | 1.1% | 0 | 1 | 0 |