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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Application site swelling: Which Medications Cause It? (3,394 Reports Across 84 Drugs)

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Application site swelling has been reported as an adverse event with 84 different drugs in the FDA's FAERS database, with 3,394 total reports. 1 of these reports resulted in death.The drugs most commonly associated with Application site swelling are INGENOL MEBUTATE, NICOTINE, and SUMATRIPTAN.

3,394
Total Reports
84
Drugs Involved
1
Deaths
130
Hospitalizations
52.3 yrs
Average Patient Age
74.4% / 25.6%
Female / Male

Which Drugs Cause Application site swelling Most Often?

Drug Reports % of Drug Reports Deaths Hosp. Life-Threat.
INGENOL MEBUTATE 489 16.2% 0 7 2
NICOTINE 431 1.3% 0 3 0
SUMATRIPTAN 191 1.1% 0 0 0
ESTRADIOL 134 0.4% 0 0 0
BUPRENORPHINE 110 0.1% 0 0 1
DICLOFENAC 90 0.1% 0 5 0
ESTRADIOL\NORETHINDRONE 90 2.1% 0 0 0
DOCOSANOL 86 1.1% 0 0 0
MINOXIDIL 85 0.1% 0 2 0
METHYLPHENIDATE 80 0.3% 0 1 0
CRISABOROLE 78 1.0% 0 1 0
PICATO 69 17.3% 0 0 0
PEGFILGRASTIM 61 0.1% 0 2 0
EVOLOCUMAB 49 0.0% 0 0 0
MECHLORETHAMINE 45 1.7% 0 6 0
FENTANYL 42 0.0% 0 0 0
SALICYLIC ACID 42 1.9% 0 6 0
ROTIGOTINE 40 0.5% 0 4 0
ETHINYL ESTRADIOL\NORELGESTROMIN 39 0.6% 0 0 0
BENZOYL PEROXIDE 34 3.2% 0 7 1

View all 84 drugs →

Top 3 Drugs Associated With Application site swelling

489 reports
431 reports
191 reports

Related Side Effects

Drug ineffective (1,049,718) Off label use (762,782) Death (660,423) Fatigue (599,248) Nausea (562,301) Diarrhoea (491,550) Pain (471,975) Headache (460,069) Dyspnoea (409,496) Dizziness (352,922)