Atypical femur fracture: Which Medications Cause It? (2,439 Reports Across 51 Drugs)
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Atypical femur fracture has been reported as an adverse event with 51 different drugs in the FDA's FAERS database, with 2,439 total reports. 28 of these reports resulted in death.The drugs most commonly associated with Atypical femur fracture are DENOSUMAB, ALENDRONATE, and ZOLEDRONIC ACID.
2,439
Total Reports
51
Drugs Involved
28
Deaths
1,094
Hospitalizations
68.0 yrs
Average Patient Age
92.9% / 7.1%
Female / Male
Which Drugs Cause Atypical femur fracture Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| DENOSUMAB | 877 | 0.6% | 14 | 316 | 2 |
| ALENDRONATE | 719 | 2.6% | 7 | 370 | 5 |
| ZOLEDRONIC ACID | 336 | 1.0% | 7 | 156 | 1 |
| RISEDRONATE | 305 | 4.5% | 4 | 139 | 10 |
| ALENDRONIC ACID | 290 | 3.6% | 2 | 142 | 4 |
| IBANDRONATE | 121 | 1.2% | 2 | 71 | 0 |
| PREDNISOLONE | 110 | 0.1% | 0 | 33 | 0 |
| PAMIDRONATE | 86 | 5.3% | 1 | 21 | 6 |
| IBANDRONIC ACID | 85 | 2.9% | 0 | 43 | 0 |
| ALENDRONATE\CHOLECALCIFEROL | 48 | 1.8% | 0 | 38 | 0 |
| PREDNISONE | 36 | 0.0% | 0 | 25 | 0 |
| METHOTREXATE | 34 | 0.0% | 0 | 25 | 0 |
| TERIPARATIDE | 32 | 0.1% | 0 | 20 | 0 |
| ROMOSOZUMAB-AQQG | 24 | 0.2% | 0 | 6 | 0 |
| ETIDRONATE | 22 | 23.2% | 0 | 9 | 0 |
| MINODRONIC ACID | 21 | 15.1% | 0 | 11 | 0 |
| FOSAMAX | 20 | 2.1% | 0 | 14 | 0 |
| PROLIA | 20 | 0.5% | 0 | 9 | 0 |
| ESOMEPRAZOLE | 19 | 0.0% | 0 | 19 | 0 |
| RISEDRONIC ACID | 19 | 4.1% | 0 | 11 | 0 |