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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Bipolar disorder: Which Medications Cause It? (6,495 Reports Across 353 Drugs)

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Bipolar disorder has been reported as an adverse event with 353 different drugs in the FDA's FAERS database, with 6,495 total reports. 161 of these reports resulted in death.The drugs most commonly associated with Bipolar disorder are SODIUM OXYBATE, QUETIAPINE, and OXYCODONE.

6,495
Total Reports
353
Drugs Involved
161
Deaths
2,352
Hospitalizations
44.4 yrs
Average Patient Age
64.1% / 35.9%
Female / Male

Which Drugs Cause Bipolar disorder Most Often?

Drug Reports % of Drug Reports Deaths Hosp. Life-Threat.
SODIUM OXYBATE 349 0.6% 1 88 0
QUETIAPINE 296 0.4% 4 124 16
OXYCODONE 280 0.2% 51 103 4
ARIPIPRAZOLE 278 0.4% 4 131 10
LURASIDONE 251 1.5% 0 59 2
ADALIMUMAB 221 0.0% 1 122 1
OLANZAPINE 205 0.4% 20 129 10
LAMOTRIGINE 189 0.4% 0 80 5
VENLAFAXINE 177 0.4% 2 69 5
ACETAMINOPHEN\HYDROCODONE 175 0.2% 24 62 3
ACETAMINOPHEN\OXYCODONE 167 0.2% 26 54 3
CLOZAPINE 148 0.2% 3 118 1
TRAMADOL 133 0.2% 15 56 3
LITHIUM 126 0.8% 5 80 7
MORPHINE 120 0.1% 17 46 1
HYDROMORPHONE 117 0.1% 18 40 2
DIVALPROEX 108 0.9% 0 63 2
DIMETHYL 104 0.1% 2 46 1
DULOXETINE 104 0.2% 0 22 5
RISPERIDONE 99 0.1% 3 51 2

View all 353 drugs →

Top 3 Drugs Associated With Bipolar disorder

349 reports
296 reports
280 reports

Related Side Effects

Drug ineffective (1,049,718) Off label use (762,782) Death (660,423) Fatigue (599,248) Nausea (562,301) Diarrhoea (491,550) Pain (471,975) Headache (460,069) Dyspnoea (409,496) Dizziness (352,922)