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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Blood creatine increased: Which Medications Cause It? (2,791 Reports Across 265 Drugs)

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Blood creatine increased has been reported as an adverse event with 265 different drugs in the FDA's FAERS database, with 2,791 total reports. 135 of these reports resulted in death.The drugs most commonly associated with Blood creatine increased are SACUBITRIL\VALSARTAN, METHOTREXATE, and EMTRICITABINE\TENOFOVIR DISOPROXIL.

2,791
Total Reports
265
Drugs Involved
135
Deaths
1,129
Hospitalizations
61.0 yrs
Average Patient Age
47.0% / 53.0%
Female / Male

Which Drugs Cause Blood creatine increased Most Often?

Drug Reports % of Drug Reports Deaths Hosp. Life-Threat.
SACUBITRIL\VALSARTAN 140 0.1% 6 27 3
METHOTREXATE 87 0.0% 2 42 6
EMTRICITABINE\TENOFOVIR DISOPROXIL 75 0.2% 2 7 0
FUROSEMIDE 72 0.1% 2 52 3
LENALIDOMIDE 70 0.0% 2 16 0
TACROLIMUS 64 0.1% 7 42 0
ATORVASTATIN 56 0.1% 0 34 3
METFORMIN 56 0.1% 3 43 7
TENOFOVIR DISOPROXIL 54 0.2% 2 9 0
FLUOROURACIL 50 0.1% 2 47 2
TRASTUZUMAB 50 0.1% 0 43 0
CYCLOPHOSPHAMIDE 49 0.0% 1 43 0
ETANERCEPT 46 0.0% 0 23 3
RITUXIMAB 46 0.0% 1 9 1
NIRAPARIB 44 0.2% 0 8 1
ROSUVASTATIN 43 0.1% 1 26 2
ADALIMUMAB 42 0.0% 1 21 0
DOCETAXEL 42 0.1% 2 39 0
CIPROFLOXACIN 41 0.1% 0 36 2
PERTUZUMAB 41 0.2% 0 38 0

View all 265 drugs →

Top 3 Drugs Associated With Blood creatine increased

140 reports
87 reports

Related Side Effects

Drug ineffective (1,049,718) Off label use (762,782) Death (660,423) Fatigue (599,248) Nausea (562,301) Diarrhoea (491,550) Pain (471,975) Headache (460,069) Dyspnoea (409,496) Dizziness (352,922)