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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Blood creatine phosphokinase increased: Which Medications Cause It? (15,579 Reports Across 730 Drugs)

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Blood creatine phosphokinase increased has been reported as an adverse event with 730 different drugs in the FDA's FAERS database, with 15,579 total reports. 811 of these reports resulted in death.The drugs most commonly associated with Blood creatine phosphokinase increased are ATORVASTATIN, SIMVASTATIN, and ROSUVASTATIN.

15,579
Total Reports
730
Drugs Involved
811
Deaths
7,647
Hospitalizations
53.2 yrs
Average Patient Age
38.8% / 61.2%
Female / Male

Which Drugs Cause Blood creatine phosphokinase increased Most Often?

Drug Reports % of Drug Reports Deaths Hosp. Life-Threat.
ATORVASTATIN 1,491 1.9% 33 660 110
SIMVASTATIN 895 3.3% 41 406 67
ROSUVASTATIN 859 2.4% 9 316 99
QUETIAPINE 663 0.9% 23 458 134
CLOZAPINE 610 0.6% 28 379 58
ARIPIPRAZOLE 594 0.9% 55 405 86
OLANZAPINE 561 1.1% 15 392 98
DAPTOMYCIN 461 5.1% 25 205 22
RISPERIDONE 402 0.5% 15 286 63
EZETIMIBE 350 2.7% 0 88 13
LEVETIRACETAM 337 0.5% 44 208 40
EVOLOCUMAB 318 0.2% 3 21 2
NIVOLUMAB 294 0.3% 49 191 41
SERTRALINE 261 0.4% 2 178 31
HALOPERIDOL 244 1.5% 6 151 56
PEMBROLIZUMAB 240 0.3% 41 156 30
DABRAFENIB 238 1.2% 26 120 12
METFORMIN 231 0.3% 3 115 17
ACETAMINOPHEN 218 0.2% 16 158 20
BRIGATINIB 198 6.0% 10 42 7

View all 730 drugs →

Top 3 Drugs Associated With Blood creatine phosphokinase increased

1,491 reports
895 reports
859 reports

Related Side Effects

Drug ineffective (1,049,718) Off label use (762,782) Death (660,423) Fatigue (599,248) Nausea (562,301) Diarrhoea (491,550) Pain (471,975) Headache (460,069) Dyspnoea (409,496) Dizziness (352,922)