Blood lactate dehydrogenase increased: Which Medications Cause It? (8,768 Reports Across 507 Drugs)
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Blood lactate dehydrogenase increased has been reported as an adverse event with 507 different drugs in the FDA's FAERS database, with 8,768 total reports. 1,317 of these reports resulted in death.The drugs most commonly associated with Blood lactate dehydrogenase increased are ECULIZUMAB, RITUXIMAB, and CYCLOPHOSPHAMIDE.
8,768
Total Reports
507
Drugs Involved
1,317
Deaths
3,920
Hospitalizations
53.7 yrs
Average Patient Age
51.3% / 48.7%
Female / Male
Which Drugs Cause Blood lactate dehydrogenase increased Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| ECULIZUMAB | 1,290 | 2.9% | 79 | 420 | 44 |
| RITUXIMAB | 929 | 0.5% | 170 | 232 | 27 |
| CYCLOPHOSPHAMIDE | 843 | 0.7% | 141 | 194 | 38 |
| VINCRISTINE | 669 | 0.9% | 95 | 130 | 16 |
| DOXORUBICIN | 667 | 0.8% | 115 | 128 | 24 |
| PREDNISONE | 636 | 0.4% | 93 | 152 | 28 |
| BENDAMUSTINE | 484 | 2.5% | 105 | 72 | 8 |
| DEXAMETHASONE | 469 | 0.4% | 121 | 110 | 32 |
| CYTARABINE | 389 | 0.9% | 73 | 77 | 14 |
| METHOTREXATE | 386 | 0.2% | 72 | 155 | 22 |
| ETOPOSIDE | 377 | 0.7% | 47 | 78 | 25 |
| RUXOLITINIB | 349 | 0.5% | 59 | 153 | 29 |
| OXALIPLATIN | 319 | 0.6% | 52 | 61 | 10 |
| POLATUZUMAB VEDOTIN | 307 | 6.5% | 66 | 49 | 7 |
| GEMCITABINE | 273 | 0.9% | 34 | 29 | 16 |
| CISPLATIN | 264 | 0.6% | 54 | 65 | 13 |
| CARBOPLATIN | 260 | 0.3% | 30 | 69 | 14 |
| VENETOCLAX | 237 | 0.4% | 39 | 108 | 9 |
| PREDNISOLONE | 233 | 0.3% | 49 | 99 | 12 |
| IFOSFAMIDE | 207 | 1.2% | 25 | 23 | 6 |