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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Bone density decreased: Which Medications Cause It? (27,951 Reports Across 291 Drugs)

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Bone density decreased has been reported as an adverse event with 291 different drugs in the FDA's FAERS database, with 27,951 total reports. 342 of these reports resulted in death.The drugs most commonly associated with Bone density decreased are EMTRICITABINE\TENOFOVIR DISOPROXIL, TENOFOVIR DISOPROXIL, and EFAVIRENZ\EMTRICITABINE\TENOFOVIR DISOPROXIL.

27,951
Total Reports
291
Drugs Involved
342
Deaths
2,260
Hospitalizations
49.9 yrs
Average Patient Age
39.1% / 60.9%
Female / Male

Which Drugs Cause Bone density decreased Most Often?

Drug Reports % of Drug Reports Deaths Hosp. Life-Threat.
EMTRICITABINE\TENOFOVIR DISOPROXIL 16,315 41.5% 191 854 0
TENOFOVIR DISOPROXIL 10,586 39.2% 159 601 0
EFAVIRENZ\EMTRICITABINE\TENOFOVIR DISOPROXIL 9,547 51.4% 92 486 0
COBICISTAT\ELVITEGRAVIR\EMTRICITABINE\TENOFOVIR DISOPROXIL 4,529 53.7% 48 221 0
EMTRICITABINE\RILPIVIRINE\TENOFOVIR DISOPROXIL 3,497 48.4% 38 156 0
TERIPARATIDE 1,178 1.7% 1 29 3
DENOSUMAB 968 0.7% 8 60 5
METHOTREXATE 599 0.2% 15 345 86
ADALIMUMAB 584 0.1% 19 358 86
TOCILIZUMAB 573 0.6% 18 331 86
PREDNISONE 553 0.4% 16 386 84
ABATACEPT 550 0.5% 11 318 86
HYDROXYCHLOROQUINE 534 0.8% 15 356 84
ETANERCEPT 477 0.1% 16 323 81
ANAKINRA 363 3.0% 0 330 69
INFLIXIMAB 362 0.3% 15 314 84
SULFASALAZINE 347 0.9% 15 310 82
NAPROXEN 308 0.6% 16 280 84
RALOXIFENE 228 5.5% 0 4 1
ALENDRONATE 227 0.8% 27 122 16

View all 291 drugs →

Top 3 Drugs Associated With Bone density decreased

10,586 reports

Related Side Effects

Drug ineffective (1,049,718) Off label use (762,782) Death (660,423) Fatigue (599,248) Nausea (562,301) Diarrhoea (491,550) Pain (471,975) Headache (460,069) Dyspnoea (409,496) Dizziness (352,922)