Botulism: Which Medications Cause It? (507 Reports Across 24 Drugs)
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Botulism has been reported as an adverse event with 24 different drugs in the FDA's FAERS database, with 507 total reports. 23 of these reports resulted in death.The drugs most commonly associated with Botulism are ONABOTULINUMTOXINA, BOTULINUM TOXIN TYPE A, and ABOBOTULINUMTOXINA.
507
Total Reports
24
Drugs Involved
23
Deaths
239
Hospitalizations
38.8 yrs
Average Patient Age
82.0% / 18.0%
Female / Male
Which Drugs Cause Botulism Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| ONABOTULINUMTOXINA | 285 | 0.6% | 9 | 124 | 27 |
| BOTULINUM TOXIN TYPE A | 86 | 2.3% | 1 | 45 | 8 |
| ABOBOTULINUMTOXINA | 26 | 0.5% | 0 | 15 | 3 |
| INCOBOTULINUMTOXINA | 26 | 0.5% | 1 | 5 | 3 |
| BOTULINUM TOXIN NOS | 18 | 6.6% | 0 | 15 | 0 |
| CIPROFLOXACIN | 13 | 0.0% | 0 | 0 | 0 |
| PIPERACILLIN\TAZOBACTAM | 13 | 0.1% | 6 | 9 | 2 |
| FOSCARNET | 10 | 0.5% | 8 | 4 | 0 |
| GANCICLOVIR | 10 | 0.2% | 7 | 4 | 0 |
| LETIBOTULINUMTOXINA-WLBG | 10 | 10.5% | 0 | 9 | 1 |
| METRONIDAZOLE | 10 | 0.0% | 6 | 4 | 0 |
| VANCOMYCIN | 10 | 0.0% | 5 | 5 | 1 |
| VALGANCICLOVIR | 9 | 0.1% | 7 | 4 | 0 |
| CEFEPIME | 8 | 0.1% | 5 | 3 | 0 |
| MICAFUNGIN | 8 | 0.3% | 5 | 3 | 0 |
| IMIPENEM | 7 | 0.4% | 4 | 3 | 0 |
| LEVOFLOXACIN | 7 | 0.0% | 4 | 3 | 0 |
| LINEZOLID | 7 | 0.0% | 4 | 3 | 0 |
| SULFAMETHOXAZOLE\TRIMETHOPRIM | 7 | 0.0% | 4 | 3 | 0 |
| HUMAN CYTOMEGALOVIRUS IMMUNE GLOBULIN | 6 | 1.6% | 4 | 3 | 0 |