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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Breakthrough covid-19: Which Medications Cause It? (228 Reports Across 26 Drugs)

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Breakthrough covid-19 has been reported as an adverse event with 26 different drugs in the FDA's FAERS database, with 228 total reports. 30 of these reports resulted in death.The drugs most commonly associated with Breakthrough covid-19 are RITUXIMAB, CILGAVIMAB\TIXAGEVIMAB, and PREDNISONE.

228
Total Reports
26
Drugs Involved
30
Deaths
101
Hospitalizations
59.3 yrs
Average Patient Age
50.0% / 50.0%
Female / Male

Which Drugs Cause Breakthrough covid-19 Most Often?

Drug Reports % of Drug Reports Deaths Hosp. Life-Threat.
RITUXIMAB 84 0.1% 13 28 14
CILGAVIMAB\TIXAGEVIMAB 51 2.4% 6 34 1
PREDNISONE 44 0.0% 8 13 4
CYCLOPHOSPHAMIDE 30 0.0% 1 7 3
VINCRISTINE 29 0.0% 0 7 3
DOXORUBICIN 26 0.0% 0 7 3
METHOTREXATE 26 0.0% 1 3 0
BENDAMUSTINE 23 0.1% 1 0 5
TOZINAMERAN 19 0.3% 3 7 0
ELASOMERAN 18 0.9% 2 4 2
MYCOPHENOLATE MOFETIL 18 0.0% 4 5 0
PREDNISOLONE 17 0.0% 1 10 4
TACROLIMUS 12 0.0% 3 6 0
NIRMATRELVIR\RITONAVIR 9 0.0% 1 1 0
AZATHIOPRINE 7 0.0% 1 6 5
HYDROXYCHLOROQUINE 7 0.0% 2 1 0
LENALIDOMIDE 7 0.0% 1 6 2
MYCOPHENOLIC ACID 7 0.0% 2 3 0
TOCILIZUMAB 7 0.0% 1 0 0
ADALIMUMAB 6 0.0% 2 4 1

View all 26 drugs →

Top 3 Drugs Associated With Breakthrough covid-19

84 reports
44 reports

Related Side Effects

Drug ineffective (1,049,718) Off label use (762,782) Death (660,423) Fatigue (599,248) Nausea (562,301) Diarrhoea (491,550) Pain (471,975) Headache (460,069) Dyspnoea (409,496) Dizziness (352,922)