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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Breakthrough haemolysis: Which Medications Cause It? (281 Reports Across 6 Drugs)

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Breakthrough haemolysis has been reported as an adverse event with 6 different drugs in the FDA's FAERS database, with 281 total reports. 6 of these reports resulted in death.The drugs most commonly associated with Breakthrough haemolysis are RAVULIZUMAB-CWVZ, ECULIZUMAB, and PEGCETACOPLAN.

281
Total Reports
6
Drugs Involved
6
Deaths
74
Hospitalizations
51.6 yrs
Average Patient Age
54.8% / 45.2%
Female / Male

Which Drugs Cause Breakthrough haemolysis Most Often?

Drug Reports % of Drug Reports Deaths Hosp. Life-Threat.
RAVULIZUMAB-CWVZ 120 1.2% 0 22 0
ECULIZUMAB 100 0.2% 2 26 0
PEGCETACOPLAN 67 4.9% 1 18 0
IPTACOPAN 22 4.7% 0 7 0
DANICOPAN 8 5.5% 0 1 0
DEFERASIROX 5 0.0% 0 4 0

View all 6 drugs →

Top 3 Drugs Associated With Breakthrough haemolysis

120 reports
100 reports
67 reports

Related Side Effects

Drug ineffective (1,049,718) Off label use (762,782) Death (660,423) Fatigue (599,248) Nausea (562,301) Diarrhoea (491,550) Pain (471,975) Headache (460,069) Dyspnoea (409,496) Dizziness (352,922)