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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

C-reactive protein increased: Which Medications Cause It? (26,428 Reports Across 1,018 Drugs)

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C-reactive protein increased has been reported as an adverse event with 1,018 different drugs in the FDA's FAERS database, with 26,428 total reports. 3,407 of these reports resulted in death.The drugs most commonly associated with C-reactive protein increased are METHOTREXATE, ADALIMUMAB, and RITUXIMAB.

26,428
Total Reports
1,018
Drugs Involved
3,407
Deaths
14,411
Hospitalizations
53.8 yrs
Average Patient Age
59.8% / 40.2%
Female / Male

Which Drugs Cause C-reactive protein increased Most Often?

Drug Reports % of Drug Reports Deaths Hosp. Life-Threat.
METHOTREXATE 5,999 2.4% 1,179 2,620 1,191
ADALIMUMAB 4,579 0.9% 1,128 2,712 1,134
RITUXIMAB 4,060 2.3% 1,148 2,304 1,068
ETANERCEPT 3,922 1.1% 911 1,932 981
TOCILIZUMAB 3,719 3.8% 1,150 2,207 1,073
INFLIXIMAB 3,621 2.6% 1,073 2,170 1,086
LEFLUNOMIDE 3,574 6.3% 1,053 1,916 1,055
HYDROXYCHLOROQUINE 3,552 5.3% 1,038 1,986 1,023
ABATACEPT 3,451 3.0% 1,016 2,027 1,103
SULFASALAZINE 3,096 7.7% 1,029 1,885 1,029
PREDNISONE 2,363 1.5% 989 1,627 955
TOFACITINIB 2,309 1.5% 929 1,203 858
SECUKINUMAB 2,224 1.5% 958 1,282 884
CERTOLIZUMAB PEGOL 1,973 2.0% 983 1,134 817
ALENDRONATE 1,685 6.0% 1,023 1,362 856
GOLIMUMAB 1,640 2.4% 930 1,128 785
ETANERCEPT-SZZS 1,627 13.7% 914 1,045 790
DICLOFENAC 1,536 1.8% 1,051 1,024 886
FOLIC ACID 1,502 6.6% 942 1,014 753
NAPROXEN 1,417 2.7% 760 1,086 727

View all 1,018 drugs →

Top 3 Drugs Associated With C-reactive protein increased

5,999 reports
4,579 reports
4,060 reports

Related Side Effects

Drug ineffective (1,049,718) Off label use (762,782) Death (660,423) Fatigue (599,248) Nausea (562,301) Diarrhoea (491,550) Pain (471,975) Headache (460,069) Dyspnoea (409,496) Dizziness (352,922)