Cauda equina syndrome: Which Medications Cause It? (504 Reports Across 55 Drugs)
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Cauda equina syndrome has been reported as an adverse event with 55 different drugs in the FDA's FAERS database, with 504 total reports. 32 of these reports resulted in death.The drugs most commonly associated with Cauda equina syndrome are BUPIVACAINE, METHOTREXATE, and LIDOCAINE.
504
Total Reports
55
Drugs Involved
32
Deaths
278
Hospitalizations
53.6 yrs
Average Patient Age
54.6% / 45.4%
Female / Male
Which Drugs Cause Cauda equina syndrome Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| BUPIVACAINE | 59 | 0.5% | 0 | 22 | 2 |
| METHOTREXATE | 42 | 0.0% | 0 | 27 | 8 |
| LIDOCAINE | 40 | 0.2% | 0 | 23 | 1 |
| PREDNISONE | 29 | 0.0% | 0 | 22 | 5 |
| ADALIMUMAB | 25 | 0.0% | 1 | 17 | 1 |
| DEXAMETHASONE | 23 | 0.0% | 1 | 16 | 0 |
| ROPIVACAINE | 21 | 0.7% | 0 | 7 | 0 |
| AMITRIPTYLINE | 17 | 0.1% | 0 | 0 | 6 |
| CYTARABINE | 17 | 0.0% | 0 | 8 | 0 |
| METHYLPREDNISOLONE | 15 | 0.0% | 0 | 13 | 0 |
| SODIUM | 15 | 0.1% | 0 | 14 | 0 |
| RITUXIMAB | 14 | 0.0% | 0 | 10 | 2 |
| TRIAMCINOLONE | 14 | 0.2% | 0 | 12 | 0 |
| FENTANYL | 13 | 0.0% | 0 | 1 | 0 |
| LETROZOLE | 13 | 0.0% | 1 | 3 | 0 |
| AMLODIPINE | 12 | 0.0% | 0 | 0 | 0 |
| CYCLOPHOSPHAMIDE | 12 | 0.0% | 1 | 8 | 3 |
| PACLITAXEL | 12 | 0.0% | 0 | 1 | 0 |
| RIBOCICLIB | 12 | 0.0% | 0 | 2 | 0 |
| TRIAMCINOLONE ACETONIDE | 12 | 0.1% | 0 | 9 | 0 |