Cerebral atrophy: Which Medications Cause It? (2,045 Reports Across 212 Drugs)
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Cerebral atrophy has been reported as an adverse event with 212 different drugs in the FDA's FAERS database, with 2,045 total reports. 185 of these reports resulted in death.The drugs most commonly associated with Cerebral atrophy are FINGOLIMOD, VALPROIC ACID, and PHENYTOIN.
2,045
Total Reports
212
Drugs Involved
185
Deaths
957
Hospitalizations
53.6 yrs
Average Patient Age
53.0% / 47.0%
Female / Male
Which Drugs Cause Cerebral atrophy Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| FINGOLIMOD | 87 | 0.1% | 1 | 19 | 3 |
| VALPROIC ACID | 84 | 0.4% | 2 | 39 | 5 |
| PHENYTOIN | 58 | 0.4% | 6 | 23 | 2 |
| METHOTREXATE | 55 | 0.0% | 3 | 28 | 5 |
| LEVETIRACETAM | 54 | 0.1% | 2 | 27 | 3 |
| CYCLOPHOSPHAMIDE | 52 | 0.0% | 12 | 28 | 12 |
| OLANZAPINE | 52 | 0.1% | 1 | 27 | 18 |
| CARBIDOPA\LEVODOPA | 50 | 0.1% | 8 | 34 | 1 |
| VALPROATE | 50 | 0.3% | 2 | 23 | 1 |
| OCRELIZUMAB | 48 | 0.1% | 0 | 11 | 1 |
| INTERFERON BETA-1A | 46 | 0.1% | 2 | 11 | 0 |
| PREDNISONE | 46 | 0.0% | 10 | 37 | 12 |
| RISPERIDONE | 45 | 0.1% | 2 | 35 | 5 |
| ADALIMUMAB | 43 | 0.0% | 3 | 27 | 3 |
| ZOMETA | 40 | 4.6% | 12 | 30 | 0 |
| LAMOTRIGINE | 39 | 0.1% | 0 | 28 | 0 |
| DIVALPROEX | 38 | 0.3% | 1 | 17 | 0 |
| QUETIAPINE | 38 | 0.1% | 1 | 21 | 1 |
| TACROLIMUS | 37 | 0.0% | 4 | 29 | 10 |
| RITUXIMAB | 36 | 0.0% | 8 | 14 | 9 |