Cerebrospinal fluid leakage: Which Medications Cause It? (1,573 Reports Across 106 Drugs)
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Cerebrospinal fluid leakage has been reported as an adverse event with 106 different drugs in the FDA's FAERS database, with 1,573 total reports. 50 of these reports resulted in death.The drugs most commonly associated with Cerebrospinal fluid leakage are BACLOFEN, ADALIMUMAB, and CABERGOLINE.
1,573
Total Reports
106
Drugs Involved
50
Deaths
716
Hospitalizations
43.1 yrs
Average Patient Age
59.7% / 40.3%
Female / Male
Which Drugs Cause Cerebrospinal fluid leakage Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| BACLOFEN | 378 | 1.5% | 5 | 136 | 9 |
| ADALIMUMAB | 88 | 0.0% | 0 | 54 | 3 |
| CABERGOLINE | 78 | 3.7% | 0 | 33 | 4 |
| NUSINERSEN | 71 | 1.0% | 0 | 31 | 0 |
| FIBRINOGEN HUMAN\THROMBIN HUMAN | 57 | 5.7% | 2 | 23 | 0 |
| MORPHINE | 42 | 0.0% | 0 | 21 | 3 |
| HYDROMORPHONE | 35 | 0.0% | 1 | 14 | 2 |
| OCTREOTIDE | 32 | 0.1% | 0 | 14 | 2 |
| BUPIVACAINE | 28 | 0.3% | 1 | 9 | 1 |
| ZICONOTIDE | 28 | 1.6% | 0 | 4 | 0 |
| GABAPENTIN | 27 | 0.0% | 0 | 5 | 0 |
| HUMAN IMMUNOGLOBULIN G | 23 | 0.0% | 0 | 14 | 1 |
| BEVACIZUMAB | 21 | 0.0% | 4 | 17 | 1 |
| METHOTREXATE | 21 | 0.0% | 0 | 14 | 0 |
| TEMOZOLOMIDE | 20 | 0.1% | 3 | 7 | 0 |
| FENTANYL | 19 | 0.0% | 0 | 5 | 0 |
| NATALIZUMAB | 19 | 0.0% | 0 | 17 | 0 |
| TRIAMCINOLONE ACETONIDE | 19 | 0.1% | 0 | 13 | 0 |
| CARMUSTINE | 18 | 0.5% | 2 | 5 | 2 |
| DEXAMETHASONE | 18 | 0.0% | 1 | 15 | 0 |