Change in seizure presentation: Which Medications Cause It? (658 Reports Across 41 Drugs)
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Change in seizure presentation has been reported as an adverse event with 41 different drugs in the FDA's FAERS database, with 658 total reports. 7 of these reports resulted in death.The drugs most commonly associated with Change in seizure presentation are LEVETIRACETAM, LACOSAMIDE, and CANNABIDIOL.
658
Total Reports
41
Drugs Involved
7
Deaths
160
Hospitalizations
26.4 yrs
Average Patient Age
55.7% / 44.3%
Female / Male
Which Drugs Cause Change in seizure presentation Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| LEVETIRACETAM | 184 | 0.3% | 2 | 40 | 4 |
| LACOSAMIDE | 100 | 0.5% | 0 | 30 | 2 |
| CANNABIDIOL | 73 | 0.4% | 0 | 23 | 1 |
| STIRIPENTOL | 47 | 3.5% | 4 | 10 | 0 |
| GANAXOLONE | 43 | 8.4% | 0 | 3 | 0 |
| CLOBAZAM | 39 | 0.4% | 0 | 19 | 1 |
| BRIVARACETAM | 34 | 0.6% | 0 | 9 | 1 |
| VIGABATRIN | 34 | 0.3% | 0 | 12 | 0 |
| LAMOTRIGINE | 33 | 0.1% | 0 | 4 | 1 |
| TOPIRAMATE | 33 | 0.1% | 0 | 8 | 0 |
| FENFLURAMINE | 28 | 0.7% | 0 | 8 | 2 |
| ZONISAMIDE | 22 | 0.5% | 0 | 15 | 1 |
| CLONAZEPAM | 20 | 0.1% | 0 | 5 | 0 |
| VALPROIC ACID | 18 | 0.1% | 0 | 10 | 0 |
| CENOBAMATE | 17 | 0.3% | 0 | 4 | 0 |
| MIDAZOLAM | 16 | 0.1% | 0 | 12 | 0 |
| CARBAMAZEPINE | 13 | 0.1% | 0 | 2 | 0 |
| ESLICARBAZEPINE | 13 | 0.4% | 0 | 2 | 0 |
| ACETAMINOPHEN | 11 | 0.0% | 0 | 11 | 0 |
| ALFENTANIL | 11 | 2.9% | 0 | 11 | 0 |