Cheilitis: Which Medications Cause It? (3,304 Reports Across 252 Drugs)
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Cheilitis has been reported as an adverse event with 252 different drugs in the FDA's FAERS database, with 3,304 total reports. 91 of these reports resulted in death.The drugs most commonly associated with Cheilitis are ISOTRETINOIN, DUPILUMAB, and METHOTREXATE.
3,304
Total Reports
252
Drugs Involved
91
Deaths
757
Hospitalizations
52.3 yrs
Average Patient Age
67.8% / 32.2%
Female / Male
Which Drugs Cause Cheilitis Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| ISOTRETINOIN | 300 | 0.9% | 3 | 11 | 0 |
| DUPILUMAB | 183 | 0.1% | 0 | 10 | 0 |
| METHOTREXATE | 101 | 0.0% | 6 | 36 | 10 |
| ADALIMUMAB | 82 | 0.0% | 0 | 16 | 0 |
| CAPECITABINE | 69 | 0.1% | 4 | 42 | 1 |
| EVEROLIMUS | 63 | 0.2% | 2 | 19 | 2 |
| DOCOSANOL | 61 | 0.8% | 0 | 0 | 0 |
| LAMOTRIGINE | 59 | 0.1% | 0 | 44 | 11 |
| SULFAMETHOXAZOLE\TRIMETHOPRIM | 59 | 0.2% | 4 | 36 | 6 |
| PALBOCICLIB | 56 | 0.1% | 1 | 4 | 0 |
| IBUPROFEN | 50 | 0.1% | 0 | 30 | 3 |
| PREDNISONE | 47 | 0.0% | 0 | 2 | 0 |
| ETANERCEPT | 44 | 0.0% | 0 | 3 | 0 |
| PEMBROLIZUMAB | 44 | 0.1% | 6 | 28 | 7 |
| IBRUTINIB | 43 | 0.1% | 1 | 14 | 0 |
| CABOZANTINIB S-MALATE | 42 | 0.1% | 1 | 6 | 0 |
| INFLIXIMAB | 42 | 0.0% | 0 | 6 | 0 |
| FLUOROURACIL | 39 | 0.1% | 1 | 15 | 1 |
| NIVOLUMAB | 38 | 0.0% | 1 | 15 | 2 |
| SECUKINUMAB | 37 | 0.0% | 0 | 7 | 4 |