Coombs positive haemolytic anaemia: Which Medications Cause It? (289 Reports Across 47 Drugs)
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Coombs positive haemolytic anaemia has been reported as an adverse event with 47 different drugs in the FDA's FAERS database, with 289 total reports. 31 of these reports resulted in death.The drugs most commonly associated with Coombs positive haemolytic anaemia are AZATHIOPRINE, CYCLOSPORINE, and RITUXIMAB.
289
Total Reports
47
Drugs Involved
31
Deaths
115
Hospitalizations
46.1 yrs
Average Patient Age
35.1% / 64.9%
Female / Male
Which Drugs Cause Coombs positive haemolytic anaemia Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| AZATHIOPRINE | 97 | 0.3% | 17 | 17 | 17 |
| CYCLOSPORINE | 93 | 0.1% | 0 | 0 | 0 |
| RITUXIMAB | 93 | 0.1% | 1 | 1 | 0 |
| PREDNISONE | 89 | 0.1% | 0 | 2 | 0 |
| DANAZOL | 87 | 18.2% | 0 | 0 | 0 |
| ROMIPLOSTIM | 87 | 1.2% | 0 | 0 | 0 |
| VINCRISTINE | 87 | 0.1% | 0 | 0 | 0 |
| DEXAMETHASONE | 86 | 0.1% | 0 | 0 | 0 |
| ASCORBIC ACID | 83 | 1.3% | 0 | 0 | 0 |
| HUMAN IMMUNOGLOBULIN G | 80 | 0.1% | 0 | 3 | 1 |
| HUMAN RHO IMMUNE GLOBULIN | 80 | 6.6% | 0 | 1 | 0 |
| CALCIUM ASCORBATE | 21 | 2.0% | 0 | 0 | 0 |
| BELIMUMAB | 20 | 0.1% | 17 | 19 | 17 |
| ACYCLOVIR | 19 | 0.1% | 17 | 19 | 17 |
| PREDNISOLONE | 19 | 0.0% | 17 | 17 | 17 |
| VALSARTAN | 18 | 0.1% | 17 | 17 | 18 |
| APIXABAN | 17 | 0.0% | 17 | 17 | 17 |
| DEXAMETHASONE\NEOMYCIN | 17 | 13.8% | 0 | 0 | 0 |
| LEVOTHYROXINE | 17 | 0.0% | 17 | 17 | 17 |
| MOLSIDOMINE | 17 | 4.4% | 17 | 17 | 17 |