Corneal perforation: Which Medications Cause It? (429 Reports Across 58 Drugs)
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Corneal perforation has been reported as an adverse event with 58 different drugs in the FDA's FAERS database, with 429 total reports. 14 of these reports resulted in death.The drugs most commonly associated with Corneal perforation are PREDNISOLONE, DEXAMETHASONE, and TOBRAMYCIN.
429
Total Reports
58
Drugs Involved
14
Deaths
146
Hospitalizations
58.9 yrs
Average Patient Age
60.2% / 39.8%
Female / Male
Which Drugs Cause Corneal perforation Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| PREDNISOLONE | 30 | 0.0% | 0 | 15 | 0 |
| DEXAMETHASONE | 26 | 0.0% | 0 | 8 | 1 |
| TOBRAMYCIN | 23 | 0.2% | 0 | 7 | 0 |
| CENEGERMIN-BKBJ | 20 | 0.2% | 0 | 0 | 0 |
| MOXIFLOXACIN | 20 | 0.1% | 0 | 8 | 0 |
| INDOMETHACIN | 19 | 0.4% | 0 | 8 | 0 |
| RITUXIMAB | 18 | 0.0% | 0 | 6 | 0 |
| VORICONAZOLE | 18 | 0.1% | 0 | 10 | 0 |
| PREDNISONE | 17 | 0.0% | 3 | 1 | 3 |
| ADALIMUMAB | 15 | 0.0% | 0 | 4 | 0 |
| BETAMETHASONE | 14 | 0.2% | 0 | 1 | 0 |
| ERLOTINIB | 14 | 0.1% | 3 | 10 | 0 |
| METHOTREXATE | 14 | 0.0% | 0 | 3 | 1 |
| TOCILIZUMAB | 14 | 0.0% | 1 | 6 | 0 |
| DOXYCYCLINE | 13 | 0.1% | 0 | 5 | 0 |
| BROMFENAC | 12 | 1.0% | 0 | 4 | 0 |
| DUPILUMAB | 12 | 0.0% | 0 | 4 | 0 |
| OFLOXACIN | 12 | 0.4% | 0 | 3 | 0 |
| BEVACIZUMAB | 11 | 0.0% | 2 | 7 | 0 |
| DICLOFENAC | 11 | 0.0% | 3 | 3 | 0 |