Cushing's syndrome: Which Medications Cause It? (2,954 Reports Across 213 Drugs)
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Cushing's syndrome has been reported as an adverse event with 213 different drugs in the FDA's FAERS database, with 2,954 total reports. 109 of these reports resulted in death.The drugs most commonly associated with Cushing's syndrome are PREDNISONE, PREDNISOLONE, and DEXAMETHASONE.
2,954
Total Reports
213
Drugs Involved
109
Deaths
908
Hospitalizations
40.4 yrs
Average Patient Age
60.1% / 39.9%
Female / Male
Which Drugs Cause Cushing's syndrome Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| PREDNISONE | 368 | 0.2% | 9 | 107 | 25 |
| PREDNISOLONE | 278 | 0.3% | 6 | 74 | 7 |
| DEXAMETHASONE | 259 | 0.2% | 10 | 77 | 8 |
| TRIAMCINOLONE ACETONIDE | 211 | 1.3% | 1 | 59 | 1 |
| METHYLPREDNISOLONE | 196 | 0.3% | 5 | 87 | 11 |
| BUDESONIDE | 190 | 0.8% | 7 | 22 | 4 |
| RITONAVIR | 170 | 1.4% | 0 | 28 | 0 |
| METHOTREXATE | 155 | 0.1% | 10 | 51 | 2 |
| FLUTICASONE | 142 | 0.4% | 0 | 19 | 0 |
| CLOBETASOL | 138 | 1.8% | 7 | 59 | 4 |
| TRIAMCINOLONE | 130 | 1.9% | 1 | 32 | 0 |
| CYCLOSPORINE | 121 | 0.2% | 2 | 31 | 1 |
| AZATHIOPRINE | 108 | 0.3% | 4 | 40 | 23 |
| MYCOPHENOLATE MOFETIL | 87 | 0.1% | 3 | 40 | 15 |
| RITUXIMAB | 85 | 0.1% | 6 | 53 | 22 |
| ADALIMUMAB | 78 | 0.0% | 0 | 27 | 2 |
| CYCLOPHOSPHAMIDE | 75 | 0.1% | 4 | 29 | 21 |
| ETANERCEPT | 74 | 0.0% | 0 | 20 | 0 |
| HYDROCORTISONE | 72 | 0.3% | 7 | 22 | 5 |
| INFLIXIMAB | 70 | 0.1% | 2 | 14 | 3 |