Decreased activity: Which Medications Cause It? (8,330 Reports Across 407 Drugs)
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Decreased activity has been reported as an adverse event with 407 different drugs in the FDA's FAERS database, with 8,330 total reports. 329 of these reports resulted in death.The drugs most commonly associated with Decreased activity are NIRAPARIB, SACUBITRIL\VALSARTAN, and RUXOLITINIB.
8,330
Total Reports
407
Drugs Involved
329
Deaths
2,200
Hospitalizations
57.3 yrs
Average Patient Age
59.6% / 40.4%
Female / Male
Which Drugs Cause Decreased activity Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| NIRAPARIB | 586 | 2.7% | 21 | 148 | 7 |
| SACUBITRIL\VALSARTAN | 570 | 0.5% | 8 | 98 | 8 |
| RUXOLITINIB | 558 | 0.8% | 9 | 71 | 1 |
| DUPILUMAB | 231 | 0.1% | 1 | 17 | 2 |
| LEVOTHYROXINE | 201 | 0.3% | 0 | 47 | 1 |
| TREPROSTINIL | 195 | 0.2% | 8 | 58 | 2 |
| PREDNISONE | 193 | 0.1% | 4 | 136 | 2 |
| ALBUTEROL | 190 | 0.2% | 14 | 128 | 1 |
| EMTRICITABINE\TENOFOVIR DISOPROXIL | 186 | 0.5% | 10 | 53 | 0 |
| TERIPARATIDE | 156 | 0.2% | 0 | 0 | 0 |
| EFAVIRENZ\EMTRICITABINE\TENOFOVIR DISOPROXIL | 145 | 0.8% | 3 | 41 | 0 |
| TIOTROPIUM | 129 | 0.3% | 13 | 101 | 0 |
| ADALIMUMAB | 128 | 0.0% | 1 | 49 | 2 |
| BUDESONIDE\FORMOTEROL | 128 | 0.4% | 4 | 73 | 2 |
| OMALIZUMAB | 123 | 0.2% | 2 | 66 | 6 |
| METHOTREXATE | 117 | 0.1% | 1 | 34 | 6 |
| TENOFOVIR DISOPROXIL | 109 | 0.4% | 5 | 28 | 0 |
| DULOXETINE | 106 | 0.2% | 0 | 20 | 6 |
| DENOSUMAB | 93 | 0.1% | 3 | 4 | 2 |
| MEPOLIZUMAB | 93 | 0.2% | 0 | 54 | 0 |