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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Depressive symptom: Which Medications Cause It? (2,579 Reports Across 272 Drugs)

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Depressive symptom has been reported as an adverse event with 272 different drugs in the FDA's FAERS database, with 2,579 total reports. 82 of these reports resulted in death.The drugs most commonly associated with Depressive symptom are QUETIAPINE, SERTRALINE, and BUPROPION.

2,579
Total Reports
272
Drugs Involved
82
Deaths
814
Hospitalizations
46.6 yrs
Average Patient Age
61.0% / 39.0%
Female / Male

Which Drugs Cause Depressive symptom Most Often?

Drug Reports % of Drug Reports Deaths Hosp. Life-Threat.
QUETIAPINE 206 0.3% 12 159 6
SERTRALINE 166 0.3% 10 124 4
BUPROPION 162 0.5% 11 119 1
RISPERIDONE 156 0.2% 14 136 2
CITALOPRAM HYDROBROMIDE 142 0.5% 3 106 2
CLONAZEPAM 133 0.3% 12 119 4
ISOTRETINOIN 128 0.4% 1 5 3
EFAVIRENZ 116 1.5% 10 114 0
ATAZANAVIR 113 2.1% 12 112 0
RALTEGRAVIR 110 1.3% 9 104 0
VALPROIC ACID 109 0.5% 10 93 2
ZOPICLONE 106 0.8% 10 101 2
ARIPIPRAZOLE 104 0.2% 2 58 8
RITONAVIR 101 0.8% 7 99 0
OLANZAPINE 100 0.2% 4 56 4
LAMIVUDINE 99 0.6% 8 90 0
MONTELUKAST 98 0.4% 0 5 2
VENLAFAXINE 97 0.2% 18 51 2
LOPINAVIR\RITONAVIR 94 1.1% 11 94 0
PREDNISONE 94 0.1% 8 24 0

View all 272 drugs →

Top 3 Drugs Associated With Depressive symptom

206 reports
166 reports
162 reports

Related Side Effects

Drug ineffective (1,049,718) Off label use (762,782) Death (660,423) Fatigue (599,248) Nausea (562,301) Diarrhoea (491,550) Pain (471,975) Headache (460,069) Dyspnoea (409,496) Dizziness (352,922)