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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Diabetic ketoacidosis: Which Medications Cause It? (18,852 Reports Across 403 Drugs)

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Diabetic ketoacidosis has been reported as an adverse event with 403 different drugs in the FDA's FAERS database, with 18,852 total reports. 825 of these reports resulted in death.The drugs most commonly associated with Diabetic ketoacidosis are EMPAGLIFLOZIN, CANAGLIFLOZIN, and DAPAGLIFLOZIN.

18,852
Total Reports
403
Drugs Involved
825
Deaths
14,412
Hospitalizations
52.0 yrs
Average Patient Age
52.8% / 47.2%
Female / Male

Which Drugs Cause Diabetic ketoacidosis Most Often?

Drug Reports % of Drug Reports Deaths Hosp. Life-Threat.
EMPAGLIFLOZIN 3,644 9.8% 85 2,610 642
CANAGLIFLOZIN 3,413 14.0% 67 2,837 424
DAPAGLIFLOZIN 1,773 8.3% 61 1,154 391
METFORMIN 1,584 1.7% 69 1,383 276
INSULIN ASPART 1,398 6.4% 28 1,102 65
INSULIN LISPRO 924 1.2% 10 765 63
INSULIN GLARGINE 776 0.8% 15 623 59
NIVOLUMAB 687 0.8% 42 557 216
DAPAGLIFLOZIN PROPANEDIOL 547 3.2% 5 384 61
PEMBROLIZUMAB 397 0.5% 32 306 148
IPILIMUMAB 358 1.0% 18 275 105
SEMAGLUTIDE 352 0.6% 11 285 33
INSULIN HUMAN 317 1.2% 8 262 29
EMPAGLIFLOZIN\METFORMIN 312 12.6% 12 251 68
TACROLIMUS 281 0.3% 11 210 56
DULAGLUTIDE 257 0.4% 2 212 26
INSULIN DEGLUDEC 248 2.2% 2 188 10
OLANZAPINE 241 0.5% 9 193 69
INSULIN DETEMIR 219 2.3% 3 193 13
PREDNISONE 212 0.1% 18 156 40

View all 403 drugs →

Top 3 Drugs Associated With Diabetic ketoacidosis

3,644 reports
3,413 reports
1,773 reports

Related Side Effects

Drug ineffective (1,049,718) Off label use (762,782) Death (660,423) Fatigue (599,248) Nausea (562,301) Diarrhoea (491,550) Pain (471,975) Headache (460,069) Dyspnoea (409,496) Dizziness (352,922)