Diffuse alveolar damage: Which Medications Cause It? (711 Reports Across 93 Drugs)
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Diffuse alveolar damage has been reported as an adverse event with 93 different drugs in the FDA's FAERS database, with 711 total reports. 491 of these reports resulted in death.The drugs most commonly associated with Diffuse alveolar damage are METHYLPREDNISOLONE, CYCLOPHOSPHAMIDE, and PREDNISONE.
711
Total Reports
93
Drugs Involved
491
Deaths
413
Hospitalizations
54.2 yrs
Average Patient Age
38.1% / 61.9%
Female / Male
Which Drugs Cause Diffuse alveolar damage Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| METHYLPREDNISOLONE | 135 | 0.2% | 127 | 55 | 39 |
| CYCLOPHOSPHAMIDE | 125 | 0.1% | 114 | 38 | 21 |
| PREDNISONE | 122 | 0.1% | 98 | 43 | 35 |
| METHOTREXATE | 112 | 0.0% | 102 | 40 | 20 |
| DEXAMETHASONE | 84 | 0.1% | 83 | 15 | 9 |
| VINCRISTINE | 78 | 0.1% | 74 | 7 | 5 |
| CYTARABINE | 76 | 0.2% | 75 | 9 | 6 |
| DAUNORUBICIN | 75 | 0.8% | 75 | 9 | 6 |
| ETOPOSIDE | 73 | 0.1% | 71 | 4 | 3 |
| LEUCOVORIN | 73 | 0.3% | 73 | 5 | 3 |
| HYDROCORTISONE | 71 | 0.3% | 71 | 3 | 3 |
| TACROLIMUS | 71 | 0.1% | 58 | 44 | 43 |
| ASPARAGINASE | 70 | 1.4% | 70 | 3 | 4 |
| MERCAPTOPURINE | 67 | 0.6% | 67 | 2 | 2 |
| PEGASPARGASE | 66 | 0.6% | 66 | 0 | 0 |
| FILGRASTIM | 65 | 0.4% | 65 | 0 | 0 |
| PREDNISOLONE | 55 | 0.1% | 49 | 46 | 34 |
| MYCOPHENOLATE MOFETIL | 46 | 0.1% | 36 | 33 | 18 |
| RITUXIMAB | 43 | 0.0% | 33 | 35 | 20 |
| CYCLOSPORINE | 32 | 0.1% | 30 | 20 | 13 |