Distributive shock: Which Medications Cause It? (1,808 Reports Across 174 Drugs)
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Distributive shock has been reported as an adverse event with 174 different drugs in the FDA's FAERS database, with 1,808 total reports. 348 of these reports resulted in death.The drugs most commonly associated with Distributive shock are AMLODIPINE, METFORMIN, and LISINOPRIL.
1,808
Total Reports
174
Drugs Involved
348
Deaths
1,585
Hospitalizations
45.1 yrs
Average Patient Age
54.6% / 45.4%
Female / Male
Which Drugs Cause Distributive shock Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| AMLODIPINE | 622 | 1.0% | 30 | 595 | 401 |
| METFORMIN | 269 | 0.3% | 42 | 249 | 173 |
| LISINOPRIL | 112 | 0.3% | 0 | 107 | 79 |
| BUPROPION | 107 | 0.3% | 2 | 103 | 66 |
| QUETIAPINE | 87 | 0.1% | 20 | 59 | 47 |
| CYCLOBENZAPRINE | 70 | 0.8% | 0 | 66 | 41 |
| TRAZODONE | 66 | 0.3% | 0 | 64 | 39 |
| ALPRAZOLAM | 63 | 0.1% | 2 | 62 | 44 |
| CARVEDILOL | 63 | 0.5% | 12 | 62 | 36 |
| TAMSULOSIN | 61 | 0.4% | 0 | 60 | 40 |
| GABAPENTIN | 60 | 0.1% | 0 | 59 | 37 |
| LAMOTRIGINE | 55 | 0.1% | 27 | 32 | 29 |
| PREDNISONE | 54 | 0.0% | 46 | 49 | 41 |
| CLONIDINE | 53 | 0.4% | 0 | 52 | 31 |
| ACETAMINOPHEN | 52 | 0.0% | 24 | 49 | 34 |
| TACROLIMUS | 51 | 0.1% | 42 | 50 | 43 |
| HYDROCHLOROTHIAZIDE | 49 | 0.2% | 0 | 47 | 35 |
| HYDROXYZINE | 49 | 0.4% | 0 | 49 | 37 |
| VENLAFAXINE | 48 | 0.1% | 0 | 46 | 34 |
| VERAPAMIL | 46 | 0.5% | 5 | 45 | 28 |