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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Drug effect decreased: Which Medications Cause It? (33,445 Reports Across 583 Drugs)

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Drug effect decreased has been reported as an adverse event with 583 different drugs in the FDA's FAERS database, with 33,445 total reports. 166 of these reports resulted in death.The drugs most commonly associated with Drug effect decreased are ETANERCEPT, ADALIMUMAB, and METHOTREXATE.

33,445
Total Reports
583
Drugs Involved
166
Deaths
2,249
Hospitalizations
52.0 yrs
Average Patient Age
61.6% / 38.4%
Female / Male

Which Drugs Cause Drug effect decreased Most Often?

Drug Reports % of Drug Reports Deaths Hosp. Life-Threat.
ETANERCEPT 6,533 1.8% 8 288 18
ADALIMUMAB 4,327 0.9% 11 606 11
METHOTREXATE 1,678 0.7% 6 176 17
FENTANYL 1,226 1.3% 6 46 3
INFLIXIMAB 1,176 0.8% 6 176 11
BUPRENORPHINE 951 1.2% 0 6 1
APREMILAST 715 0.5% 0 9 0
HYDROXYCHLOROQUINE 625 0.9% 0 92 5
TOCILIZUMAB 601 0.6% 6 113 10
GOLIMUMAB 583 0.8% 0 43 0
ABATACEPT 525 0.5% 2 69 5
LEFLUNOMIDE 520 0.9% 0 44 4
LISDEXAMFETAMINE DIMESYLATE 496 2.9% 0 3 0
USTEKINUMAB 460 0.5% 0 44 1
METHYLPHENIDATE 451 1.5% 1 5 1
SECUKINUMAB 421 0.3% 0 16 1
TOFACITINIB 408 0.3% 1 35 6
RITUXIMAB 403 0.2% 6 58 4
OXYCODONE 378 0.2% 0 41 1
DALFAMPRIDINE 366 0.7% 0 26 0

View all 583 drugs →

Top 3 Drugs Associated With Drug effect decreased

6,533 reports
4,327 reports
1,678 reports

Related Side Effects

Drug ineffective (1,049,718) Off label use (762,782) Death (660,423) Fatigue (599,248) Nausea (562,301) Diarrhoea (491,550) Pain (471,975) Headache (460,069) Dyspnoea (409,496) Dizziness (352,922)