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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Drug level decreased: Which Medications Cause It? (8,007 Reports Across 232 Drugs)

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Drug level decreased has been reported as an adverse event with 232 different drugs in the FDA's FAERS database, with 8,007 total reports. 150 of these reports resulted in death.The drugs most commonly associated with Drug level decreased are INFLIXIMAB, INFLIXIMAB-DYYB, and ADALIMUMAB.

8,007
Total Reports
232
Drugs Involved
150
Deaths
2,256
Hospitalizations
42.5 yrs
Average Patient Age
48.5% / 51.5%
Female / Male

Which Drugs Cause Drug level decreased Most Often?

Drug Reports % of Drug Reports Deaths Hosp. Life-Threat.
INFLIXIMAB 1,401 1.0% 15 372 6
INFLIXIMAB-DYYB 1,207 4.7% 13 386 8
ADALIMUMAB 1,186 0.2% 4 411 4
VEDOLIZUMAB 937 1.3% 5 204 0
USTEKINUMAB 340 0.4% 3 44 0
TACROLIMUS 274 0.3% 9 77 15
EVEROLIMUS 161 0.4% 2 43 15
VORICONAZOLE 146 1.0% 9 52 4
LEVETIRACETAM 144 0.2% 1 31 3
LAMOTRIGINE 142 0.3% 6 34 9
PHENYTOIN 135 0.9% 2 39 3
METHOTREXATE 101 0.0% 4 44 2
PREDNISONE 95 0.1% 4 47 8
CARBAMAZEPINE 85 0.4% 3 23 3
CLOZAPINE 85 0.1% 1 42 2
MYCOPHENOLATE MOFETIL 78 0.1% 1 45 11
VALPROIC ACID 76 0.4% 2 38 0
QUETIAPINE 75 0.1% 1 53 3
DIVALPROEX 71 0.6% 0 20 2
RIFAMPIN 70 0.5% 2 37 5

View all 232 drugs →

Top 3 Drugs Associated With Drug level decreased

1,401 reports
1,207 reports
1,186 reports

Related Side Effects

Drug ineffective (1,049,718) Off label use (762,782) Death (660,423) Fatigue (599,248) Nausea (562,301) Diarrhoea (491,550) Pain (471,975) Headache (460,069) Dyspnoea (409,496) Dizziness (352,922)