Drug reaction with eosinophilia and systemic symptoms: Which Medications Cause It? (22,024 Reports Across 765 Drugs)
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Drug reaction with eosinophilia and systemic symptoms has been reported as an adverse event with 765 different drugs in the FDA's FAERS database, with 22,024 total reports. 1,426 of these reports resulted in death.The drugs most commonly associated with Drug reaction with eosinophilia and systemic symptoms are ALLOPURINOL, VANCOMYCIN, and LAMOTRIGINE.
22,024
Total Reports
765
Drugs Involved
1,426
Deaths
14,386
Hospitalizations
49.7 yrs
Average Patient Age
52.7% / 47.3%
Female / Male
Which Drugs Cause Drug reaction with eosinophilia and systemic symptoms Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| ALLOPURINOL | 2,943 | 15.5% | 319 | 2,098 | 410 |
| VANCOMYCIN | 2,509 | 7.4% | 180 | 1,465 | 471 |
| LAMOTRIGINE | 2,235 | 4.7% | 104 | 1,616 | 310 |
| SULFAMETHOXAZOLE\TRIMETHOPRIM | 1,625 | 4.2% | 111 | 1,144 | 239 |
| PIPERACILLIN\TAZOBACTAM | 1,157 | 6.0% | 81 | 762 | 198 |
| CARBAMAZEPINE | 1,149 | 4.7% | 51 | 774 | 139 |
| RIFAMPIN | 1,049 | 7.9% | 53 | 625 | 103 |
| AMOXICILLIN | 892 | 3.0% | 36 | 568 | 121 |
| CEFTRIAXONE | 793 | 4.1% | 79 | 483 | 109 |
| LEVETIRACETAM | 793 | 1.3% | 66 | 540 | 181 |
| LEVOFLOXACIN | 752 | 1.9% | 58 | 530 | 76 |
| CIPROFLOXACIN | 711 | 1.6% | 46 | 504 | 100 |
| PANTOPRAZOLE | 677 | 0.9% | 70 | 518 | 62 |
| PHENYTOIN | 673 | 4.7% | 44 | 444 | 93 |
| ACETAMINOPHEN | 637 | 0.5% | 63 | 482 | 129 |
| MEROPENEM | 626 | 4.5% | 59 | 418 | 137 |
| ISONIAZID | 550 | 7.2% | 26 | 262 | 58 |
| FUROSEMIDE | 536 | 1.0% | 61 | 412 | 49 |
| ETHAMBUTOL | 515 | 6.9% | 33 | 243 | 38 |
| ENOXAPARIN | 514 | 2.1% | 25 | 390 | 60 |