Ejection fraction decreased: Which Medications Cause It? (10,954 Reports Across 482 Drugs)
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Ejection fraction decreased has been reported as an adverse event with 482 different drugs in the FDA's FAERS database, with 10,954 total reports. 940 of these reports resulted in death.The drugs most commonly associated with Ejection fraction decreased are SACUBITRIL\VALSARTAN, TRASTUZUMAB, and DOXORUBICIN.
10,954
Total Reports
482
Drugs Involved
940
Deaths
4,565
Hospitalizations
57.3 yrs
Average Patient Age
50.1% / 49.9%
Female / Male
Which Drugs Cause Ejection fraction decreased Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| SACUBITRIL\VALSARTAN | 2,551 | 2.3% | 121 | 670 | 88 |
| TRASTUZUMAB | 1,579 | 3.4% | 157 | 417 | 77 |
| DOXORUBICIN | 834 | 1.0% | 87 | 229 | 59 |
| CYCLOPHOSPHAMIDE | 754 | 0.6% | 65 | 241 | 48 |
| PERTUZUMAB | 644 | 2.9% | 64 | 225 | 30 |
| DOCETAXEL | 520 | 0.8% | 47 | 218 | 23 |
| PACLITAXEL | 466 | 0.6% | 37 | 147 | 22 |
| BISOPROLOL | 314 | 1.1% | 20 | 229 | 25 |
| RITUXIMAB | 296 | 0.2% | 28 | 103 | 24 |
| CARVEDILOL | 284 | 2.1% | 12 | 121 | 11 |
| FUROSEMIDE | 283 | 0.6% | 11 | 174 | 13 |
| VINCRISTINE | 278 | 0.4% | 25 | 91 | 24 |
| METOPROLOL | 275 | 0.7% | 17 | 136 | 18 |
| FLUOROURACIL | 256 | 0.5% | 14 | 132 | 22 |
| CARBOPLATIN | 253 | 0.3% | 19 | 84 | 9 |
| ATORVASTATIN | 249 | 0.3% | 9 | 158 | 7 |
| EPIRUBICIN | 247 | 1.5% | 17 | 93 | 10 |
| ASPIRIN | 244 | 0.3% | 10 | 173 | 11 |
| CAPECITABINE | 241 | 0.4% | 20 | 106 | 30 |
| PREDNISONE | 240 | 0.2% | 22 | 77 | 15 |