Endocrine ophthalmopathy: Which Medications Cause It? (656 Reports Across 39 Drugs)
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Endocrine ophthalmopathy has been reported as an adverse event with 39 different drugs in the FDA's FAERS database, with 656 total reports. 5 of these reports resulted in death.The drugs most commonly associated with Endocrine ophthalmopathy are TEPROTUMUMAB-TRBW, PREDNISONE, and ALEMTUZUMAB.
656
Total Reports
39
Drugs Involved
5
Deaths
94
Hospitalizations
55.6 yrs
Average Patient Age
73.0% / 27.0%
Female / Male
Which Drugs Cause Endocrine ophthalmopathy Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| TEPROTUMUMAB-TRBW | 245 | 5.0% | 0 | 24 | 0 |
| PREDNISONE | 85 | 0.1% | 3 | 12 | 0 |
| ALEMTUZUMAB | 55 | 0.4% | 0 | 18 | 3 |
| SODIUM IODIDE I-131 | 43 | 11.6% | 0 | 1 | 1 |
| LEVOTHYROXINE | 27 | 0.0% | 0 | 6 | 0 |
| METHOTREXATE | 26 | 0.0% | 0 | 5 | 0 |
| TOCILIZUMAB | 24 | 0.0% | 0 | 3 | 0 |
| ABATACEPT | 22 | 0.0% | 0 | 2 | 0 |
| ATORVASTATIN | 21 | 0.0% | 0 | 2 | 0 |
| SIMVASTATIN | 20 | 0.1% | 0 | 2 | 0 |
| SULFASALAZINE | 20 | 0.1% | 0 | 2 | 0 |
| LEFLUNOMIDE | 19 | 0.0% | 0 | 2 | 0 |
| ROSUVASTATIN | 19 | 0.1% | 0 | 1 | 0 |
| TEPROTUMUMAB | 19 | 12.7% | 0 | 1 | 0 |
| RITUXIMAB | 18 | 0.0% | 3 | 3 | 0 |
| METHIMAZOLE | 15 | 0.6% | 0 | 3 | 1 |
| CYCLOPHOSPHAMIDE | 14 | 0.0% | 3 | 2 | 0 |
| METHYLPREDNISOLONE | 12 | 0.0% | 3 | 0 | 3 |
| ADALIMUMAB | 9 | 0.0% | 0 | 3 | 1 |
| DOXORUBICIN | 9 | 0.0% | 3 | 1 | 0 |