Extremity contracture: Which Medications Cause It? (388 Reports Across 37 Drugs)
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Extremity contracture has been reported as an adverse event with 37 different drugs in the FDA's FAERS database, with 388 total reports. 15 of these reports resulted in death.The drugs most commonly associated with Extremity contracture are METHOTREXATE, ADALIMUMAB, and TOFACITINIB.
388
Total Reports
37
Drugs Involved
15
Deaths
115
Hospitalizations
53.3 yrs
Average Patient Age
67.1% / 32.9%
Female / Male
Which Drugs Cause Extremity contracture Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| METHOTREXATE | 74 | 0.0% | 0 | 2 | 0 |
| ADALIMUMAB | 68 | 0.0% | 0 | 5 | 0 |
| TOFACITINIB | 63 | 0.0% | 0 | 3 | 0 |
| ETANERCEPT | 59 | 0.0% | 0 | 1 | 0 |
| LEFLUNOMIDE | 55 | 0.1% | 0 | 1 | 0 |
| HYDROXYCHLOROQUINE | 51 | 0.1% | 0 | 0 | 0 |
| TOCILIZUMAB | 50 | 0.1% | 0 | 0 | 0 |
| SULFASALAZINE | 47 | 0.1% | 0 | 0 | 0 |
| CERTOLIZUMAB PEGOL | 46 | 0.1% | 0 | 0 | 0 |
| GOLIMUMAB | 44 | 0.1% | 0 | 0 | 0 |
| ABATACEPT | 38 | 0.0% | 0 | 0 | 0 |
| AZATHIOPRINE | 14 | 0.0% | 0 | 3 | 0 |
| CYCLOSPORINE | 13 | 0.0% | 0 | 4 | 0 |
| PREDNISOLONE | 12 | 0.0% | 0 | 3 | 0 |
| CARBIDOPA\LEVODOPA | 11 | 0.0% | 1 | 5 | 0 |
| CYCLOPHOSPHAMIDE | 11 | 0.0% | 0 | 2 | 0 |
| MYCOPHENOLATE MOFETIL | 11 | 0.0% | 0 | 3 | 0 |
| ALDESLEUKIN | 10 | 1.2% | 0 | 2 | 0 |
| BUDESONIDE | 10 | 0.0% | 0 | 2 | 0 |
| BUSULFAN | 10 | 0.1% | 0 | 2 | 0 |