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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Fournier's gangrene: Which Medications Cause It? (2,177 Reports Across 94 Drugs)

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Fournier's gangrene has been reported as an adverse event with 94 different drugs in the FDA's FAERS database, with 2,177 total reports. 222 of these reports resulted in death.The drugs most commonly associated with Fournier's gangrene are EMPAGLIFLOZIN, CANAGLIFLOZIN, and DAPAGLIFLOZIN PROPANEDIOL.

2,177
Total Reports
94
Drugs Involved
222
Deaths
1,592
Hospitalizations
58.7 yrs
Average Patient Age
22.7% / 77.3%
Female / Male

Which Drugs Cause Fournier's gangrene Most Often?

Drug Reports % of Drug Reports Deaths Hosp. Life-Threat.
EMPAGLIFLOZIN 1,000 2.7% 63 681 252
CANAGLIFLOZIN 267 1.1% 15 232 53
DAPAGLIFLOZIN PROPANEDIOL 195 1.2% 9 148 32
DAPAGLIFLOZIN 183 0.9% 31 134 72
EMPAGLIFLOZIN\METFORMIN 71 2.9% 4 53 19
METFORMIN 64 0.1% 16 56 16
BEVACIZUMAB 47 0.1% 19 38 4
DAPAGLIFLOZIN PROPANEDIOL\METFORMIN 41 1.8% 6 35 10
DEXAMETHASONE 31 0.0% 14 22 16
PREDNISOLONE 30 0.0% 10 23 19
CANAGLIFLOZIN\METFORMIN 21 1.4% 3 20 4
CAPECITABINE 21 0.0% 13 19 3
EMPAGLIFLOZIN\LINAGLIPTIN 21 1.3% 2 16 3
FLUOROURACIL 21 0.0% 13 20 3
METHOTREXATE 20 0.0% 1 13 8
IRINOTECAN 19 0.1% 12 18 2
OXALIPLATIN 19 0.0% 10 18 5
LEUCOVORIN 17 0.1% 13 17 2
CIPROFLOXACIN 16 0.0% 3 16 8
METHYLPREDNISOLONE 16 0.0% 16 13 12

View all 94 drugs →

Top 3 Drugs Associated With Fournier's gangrene

1,000 reports
267 reports

Related Side Effects

Drug ineffective (1,049,718) Off label use (762,782) Death (660,423) Fatigue (599,248) Nausea (562,301) Diarrhoea (491,550) Pain (471,975) Headache (460,069) Dyspnoea (409,496) Dizziness (352,922)