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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Gastrointestinal injury: Which Medications Cause It? (1,789 Reports Across 85 Drugs)

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Gastrointestinal injury has been reported as an adverse event with 85 different drugs in the FDA's FAERS database, with 1,789 total reports. 84 of these reports resulted in death.The drugs most commonly associated with Gastrointestinal injury are ISOTRETINOIN, ADALIMUMAB, and CAPECITABINE.

1,789
Total Reports
85
Drugs Involved
84
Deaths
608
Hospitalizations
46.8 yrs
Average Patient Age
49.6% / 50.4%
Female / Male

Which Drugs Cause Gastrointestinal injury Most Often?

Drug Reports % of Drug Reports Deaths Hosp. Life-Threat.
ISOTRETINOIN 614 1.8% 0 64 1
ADALIMUMAB 100 0.0% 2 62 2
CAPECITABINE 68 0.1% 10 12 2
LEVONORGESTREL 66 0.1% 0 47 4
DOXYCYCLINE 62 0.4% 0 3 0
ACCUTANE 59 21.6% 0 29 0
SEVELAMER 51 0.9% 1 31 1
DOXYCYCLINE HYCLATE 30 0.5% 0 5 2
PREDNISONE 23 0.0% 1 18 2
CARBIDOPA\LEVODOPA 22 0.0% 4 17 1
CARBOPLATIN 22 0.0% 0 9 0
METHOTREXATE 21 0.0% 1 13 0
ETOPOSIDE 20 0.0% 0 5 0
IBUPROFEN 20 0.0% 0 4 1
TACROLIMUS 20 0.0% 0 15 3
TOCILIZUMAB 20 0.0% 3 13 3
ASPIRIN 19 0.0% 1 6 1
MORPHINE 19 0.0% 7 8 6
MELPHALAN 18 0.1% 0 5 0
OXYCODONE 18 0.0% 1 5 1

View all 85 drugs →

Top 3 Drugs Associated With Gastrointestinal injury

614 reports
100 reports
68 reports

Related Side Effects

Drug ineffective (1,049,718) Off label use (762,782) Death (660,423) Fatigue (599,248) Nausea (562,301) Diarrhoea (491,550) Pain (471,975) Headache (460,069) Dyspnoea (409,496) Dizziness (352,922)