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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

General physical health deterioration: Which Medications Cause It? (83,630 Reports Across 1,752 Drugs)

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General physical health deterioration has been reported as an adverse event with 1,752 different drugs in the FDA's FAERS database, with 83,630 total reports. 20,494 of these reports resulted in death.The drugs most commonly associated with General physical health deterioration are METHOTREXATE, ADALIMUMAB, and INFLIXIMAB.

83,630
Total Reports
1,752
Drugs Involved
20,494
Deaths
43,941
Hospitalizations
61.1 yrs
Average Patient Age
56.1% / 43.9%
Female / Male

Which Drugs Cause General physical health deterioration Most Often?

Drug Reports % of Drug Reports Deaths Hosp. Life-Threat.
METHOTREXATE 5,767 2.3% 2,149 3,176 2,220
ADALIMUMAB 5,718 1.1% 2,079 3,248 2,104
INFLIXIMAB 5,403 3.9% 1,848 2,628 2,016
RITUXIMAB 5,178 2.9% 2,291 3,229 2,204
ABATACEPT 4,832 4.2% 1,705 2,329 2,046
LEFLUNOMIDE 4,420 7.8% 1,899 2,525 2,202
PREDNISONE 4,402 2.8% 1,973 2,683 2,084
LUTETIUM LU-177 VIPIVOTIDE TETRAXETAN 4,332 40.4% 93 125 6
TOCILIZUMAB 4,254 4.3% 1,991 2,417 1,992
ETANERCEPT 3,898 1.1% 1,480 2,028 1,608
CERTOLIZUMAB PEGOL 3,839 3.9% 1,791 2,121 1,920
DICLOFENAC 3,834 4.4% 1,975 2,388 2,118
HYDROXYCHLOROQUINE 3,761 5.6% 1,783 2,174 1,904
SULFASALAZINE 3,749 9.3% 1,700 2,109 1,875
GOLIMUMAB 3,681 5.3% 1,730 2,082 1,892
CARBIDOPA\LEVODOPA 3,636 6.2% 1,623 2,127 102
ALENDRONATE 3,600 12.9% 1,884 2,257 2,054
FOLIC ACID 3,598 15.7% 1,867 2,141 1,985
ACETAMINOPHEN 3,594 2.6% 2,012 2,372 2,026
TOFACITINIB 3,525 2.3% 1,610 1,928 1,775

View all 1,752 drugs →

Top 3 Drugs Associated With General physical health deterioration

5,767 reports
5,718 reports
5,403 reports

Related Side Effects

Drug ineffective (1,049,718) Off label use (762,782) Death (660,423) Fatigue (599,248) Nausea (562,301) Diarrhoea (491,550) Pain (471,975) Headache (460,069) Dyspnoea (409,496) Dizziness (352,922)