Gliosis: Which Medications Cause It? (250 Reports Across 33 Drugs)
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Gliosis has been reported as an adverse event with 33 different drugs in the FDA's FAERS database, with 250 total reports. 27 of these reports resulted in death.The drugs most commonly associated with Gliosis are ADALIMUMAB, METHOTREXATE, and CHLORPROMAZINE.
250
Total Reports
33
Drugs Involved
27
Deaths
116
Hospitalizations
47.9 yrs
Average Patient Age
55.0% / 45.0%
Female / Male
Which Drugs Cause Gliosis Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| ADALIMUMAB | 31 | 0.0% | 2 | 8 | 0 |
| METHOTREXATE | 19 | 0.0% | 1 | 12 | 1 |
| CHLORPROMAZINE | 17 | 0.4% | 0 | 0 | 0 |
| HYDRALAZINE | 17 | 0.3% | 0 | 0 | 0 |
| METHYLDOPA | 17 | 0.7% | 0 | 0 | 0 |
| MINOCYCLINE | 17 | 0.3% | 0 | 0 | 0 |
| PROCAINAMIDE | 17 | 7.5% | 0 | 0 | 0 |
| VORICONAZOLE | 17 | 0.1% | 0 | 0 | 0 |
| TERBINAFINE | 16 | 0.2% | 0 | 0 | 0 |
| QUINIDINE | 15 | 4.6% | 0 | 0 | 0 |
| CARBOPLATIN | 14 | 0.0% | 1 | 8 | 0 |
| PHENYTOIN | 13 | 0.1% | 1 | 6 | 1 |
| LEVETIRACETAM | 10 | 0.0% | 1 | 5 | 1 |
| ETOPOSIDE | 9 | 0.0% | 1 | 4 | 0 |
| TACROLIMUS | 9 | 0.0% | 1 | 7 | 0 |
| INFLIXIMAB | 8 | 0.0% | 0 | 8 | 0 |
| PEMBROLIZUMAB | 8 | 0.0% | 0 | 8 | 0 |
| VINCRISTINE | 8 | 0.0% | 0 | 6 | 1 |
| CYCLOPHOSPHAMIDE | 7 | 0.0% | 4 | 4 | 0 |
| IRINOTECAN | 7 | 0.0% | 0 | 2 | 0 |