Granulomatous liver disease: Which Medications Cause It? (394 Reports Across 60 Drugs)
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Granulomatous liver disease has been reported as an adverse event with 60 different drugs in the FDA's FAERS database, with 394 total reports. 35 of these reports resulted in death.The drugs most commonly associated with Granulomatous liver disease are METHOTREXATE, ADALIMUMAB, and INFLIXIMAB.
394
Total Reports
60
Drugs Involved
35
Deaths
245
Hospitalizations
54.8 yrs
Average Patient Age
47.2% / 52.8%
Female / Male
Which Drugs Cause Granulomatous liver disease Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| METHOTREXATE | 46 | 0.0% | 2 | 39 | 5 |
| ADALIMUMAB | 35 | 0.0% | 1 | 31 | 3 |
| INFLIXIMAB | 27 | 0.0% | 1 | 23 | 5 |
| RIFAMPIN | 24 | 0.2% | 13 | 22 | 15 |
| SULFAMETHOXAZOLE\TRIMETHOPRIM | 22 | 0.1% | 0 | 9 | 2 |
| ISONIAZID | 21 | 0.3% | 13 | 19 | 15 |
| PYRAZINAMIDE | 19 | 0.3% | 13 | 18 | 15 |
| BACILLUS CALMETTE-GUERIN ANTIGEN, UNSPECIFIED SUBSTRAIN | 18 | 4.3% | 1 | 15 | 1 |
| ETHAMBUTOL | 17 | 0.2% | 13 | 15 | 15 |
| ETANERCEPT | 16 | 0.0% | 9 | 14 | 9 |
| AMPHOTERICIN B | 15 | 0.1% | 14 | 14 | 13 |
| AZATHIOPRINE | 15 | 0.1% | 0 | 13 | 0 |
| METHYLPREDNISOLONE | 15 | 0.0% | 13 | 14 | 13 |
| ACETAMINOPHEN | 14 | 0.0% | 0 | 14 | 0 |
| ATORVASTATIN | 14 | 0.0% | 0 | 2 | 0 |
| TACROLIMUS | 14 | 0.0% | 0 | 11 | 0 |
| ACYCLOVIR | 13 | 0.1% | 13 | 13 | 13 |
| CIPROFLOXACIN | 13 | 0.0% | 0 | 13 | 0 |
| PREDNISOLONE | 13 | 0.0% | 0 | 13 | 1 |
| FUROSEMIDE | 12 | 0.0% | 0 | 12 | 0 |