Hepatitis b reactivation: Which Medications Cause It? (2,999 Reports Across 144 Drugs)
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Hepatitis b reactivation has been reported as an adverse event with 144 different drugs in the FDA's FAERS database, with 2,999 total reports. 660 of these reports resulted in death.The drugs most commonly associated with Hepatitis b reactivation are RITUXIMAB, CYCLOPHOSPHAMIDE, and DOXORUBICIN.
2,999
Total Reports
144
Drugs Involved
660
Deaths
627
Hospitalizations
60.6 yrs
Average Patient Age
43.7% / 56.3%
Female / Male
Which Drugs Cause Hepatitis b reactivation Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| RITUXIMAB | 914 | 0.5% | 374 | 220 | 41 |
| CYCLOPHOSPHAMIDE | 801 | 0.6% | 315 | 198 | 38 |
| DOXORUBICIN | 684 | 0.8% | 270 | 171 | 34 |
| VINCRISTINE | 641 | 0.9% | 253 | 155 | 22 |
| PREDNISONE | 583 | 0.4% | 218 | 192 | 34 |
| PREDNISOLONE | 465 | 0.6% | 181 | 134 | 25 |
| LAMIVUDINE | 308 | 1.9% | 50 | 39 | 15 |
| METHOTREXATE | 305 | 0.1% | 62 | 51 | 8 |
| DEXAMETHASONE | 293 | 0.2% | 126 | 115 | 9 |
| ETOPOSIDE | 213 | 0.4% | 102 | 105 | 11 |
| TENOFOVIR DISOPROXIL | 162 | 0.6% | 27 | 25 | 2 |
| SOFOSBUVIR | 130 | 0.8% | 1 | 13 | 0 |
| MYCOPHENOLATE MOFETIL | 126 | 0.2% | 26 | 33 | 14 |
| PACLITAXEL | 122 | 0.2% | 76 | 82 | 5 |
| RIBAVIRIN | 109 | 0.3% | 4 | 25 | 0 |
| CYTARABINE | 105 | 0.2% | 14 | 22 | 0 |
| BEVACIZUMAB | 103 | 0.1% | 70 | 77 | 0 |
| BLEOMYCIN | 102 | 1.5% | 80 | 80 | 11 |
| DOCETAXEL | 100 | 0.2% | 86 | 62 | 0 |
| ABATACEPT | 98 | 0.1% | 4 | 8 | 1 |