Hepatocellular carcinoma: Which Medications Cause It? (6,717 Reports Across 178 Drugs)
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Hepatocellular carcinoma has been reported as an adverse event with 178 different drugs in the FDA's FAERS database, with 6,717 total reports. 1,825 of these reports resulted in death.The drugs most commonly associated with Hepatocellular carcinoma are SORAFENIB, RIBAVIRIN, and SOFOSBUVIR.
6,717
Total Reports
178
Drugs Involved
1,825
Deaths
1,662
Hospitalizations
63.1 yrs
Average Patient Age
24.2% / 75.8%
Female / Male
Which Drugs Cause Hepatocellular carcinoma Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| SORAFENIB | 1,665 | 15.3% | 492 | 306 | 40 |
| RIBAVIRIN | 1,046 | 2.4% | 151 | 263 | 78 |
| SOFOSBUVIR | 877 | 5.1% | 119 | 198 | 65 |
| LEDIPASVIR\SOFOSBUVIR | 640 | 2.7% | 76 | 136 | 26 |
| BEVACIZUMAB | 532 | 0.7% | 285 | 72 | 19 |
| REGORAFENIB | 470 | 5.0% | 99 | 67 | 3 |
| DACLATASVIR | 419 | 7.5% | 71 | 126 | 39 |
| ATEZOLIZUMAB | 342 | 1.0% | 191 | 67 | 11 |
| CABOZANTINIB S-MALATE | 219 | 0.6% | 72 | 27 | 2 |
| TACROLIMUS | 183 | 0.2% | 86 | 38 | 7 |
| SOFOSBUVIR\VELPATASVIR | 161 | 0.9% | 24 | 35 | 13 |
| OMBITASVIR\PARITAPREVIR\RITONAVIR | 154 | 3.4% | 28 | 55 | 11 |
| DASABUVIR | 147 | 3.7% | 32 | 41 | 10 |
| SIMEPREVIR | 145 | 2.4% | 28 | 43 | 5 |
| MYCOPHENOLATE MOFETIL | 117 | 0.2% | 57 | 13 | 0 |
| LAMIVUDINE | 96 | 0.6% | 34 | 23 | 3 |
| TENOFOVIR DISOPROXIL | 96 | 0.4% | 35 | 22 | 5 |
| PEGINTERFERON ALFA-2A | 95 | 0.4% | 16 | 25 | 2 |
| ENTECAVIR | 94 | 2.1% | 41 | 40 | 4 |
| PEGINTERFERON ALFA-2B | 93 | 2.2% | 15 | 33 | 1 |