Hereditary angioedema: Which Medications Cause It? (9,051 Reports Across 67 Drugs)
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Hereditary angioedema has been reported as an adverse event with 67 different drugs in the FDA's FAERS database, with 9,051 total reports. 89 of these reports resulted in death.The drugs most commonly associated with Hereditary angioedema are HUMAN C1-ESTERASE INHIBITOR, ICATIBANT, and LANADELUMAB.
9,051
Total Reports
67
Drugs Involved
89
Deaths
3,193
Hospitalizations
41.7 yrs
Average Patient Age
81.8% / 18.2%
Female / Male
Which Drugs Cause Hereditary angioedema Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| HUMAN C1-ESTERASE INHIBITOR | 5,572 | 38.9% | 26 | 1,443 | 120 |
| ICATIBANT | 2,221 | 41.4% | 45 | 1,154 | 114 |
| LANADELUMAB | 1,343 | 65.3% | 41 | 728 | 43 |
| LANADELUMAB-FLYO | 794 | 53.2% | 13 | 311 | 44 |
| ECALLANTIDE | 519 | 43.0% | 8 | 335 | 13 |
| BEROTRALSTAT | 124 | 22.6% | 1 | 52 | 3 |
| CINRYZE | 119 | 84.4% | 1 | 81 | 0 |
| OMALIZUMAB | 59 | 0.1% | 0 | 17 | 25 |
| HUMAN IMMUNOGLOBULIN G | 47 | 0.1% | 1 | 21 | 1 |
| KALBITOR | 45 | 43.7% | 0 | 35 | 0 |
| BERINERT | 30 | 55.6% | 0 | 9 | 0 |
| DUPILUMAB | 29 | 0.0% | 0 | 10 | 1 |
| RITUXIMAB | 29 | 0.0% | 0 | 2 | 1 |
| CINRYZE ) | 26 | 46.4% | 0 | 21 | 0 |
| CLONAZEPAM | 23 | 0.1% | 0 | 0 | 23 |
| DIAZEPAM | 23 | 0.1% | 0 | 0 | 23 |
| METHOTREXATE | 22 | 0.0% | 1 | 8 | 0 |
| CINRYZE ) ) | 20 | 95.2% | 0 | 18 | 0 |
| PREDNISONE | 20 | 0.0% | 0 | 4 | 0 |
| ETANERCEPT | 18 | 0.0% | 0 | 3 | 0 |