Hypertensive cardiomyopathy: Which Medications Cause It? (171 Reports Across 22 Drugs)
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Hypertensive cardiomyopathy has been reported as an adverse event with 22 different drugs in the FDA's FAERS database, with 171 total reports. 54 of these reports resulted in death.The drugs most commonly associated with Hypertensive cardiomyopathy are METHOTREXATE, CYCLOSPORINE, and TOCILIZUMAB.
171
Total Reports
22
Drugs Involved
54
Deaths
93
Hospitalizations
58.7 yrs
Average Patient Age
60.4% / 39.6%
Female / Male
Which Drugs Cause Hypertensive cardiomyopathy Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| METHOTREXATE | 20 | 0.0% | 0 | 13 | 1 |
| CYCLOSPORINE | 19 | 0.0% | 1 | 12 | 0 |
| TOCILIZUMAB | 18 | 0.0% | 1 | 11 | 0 |
| TOFACITINIB | 18 | 0.0% | 1 | 10 | 0 |
| ANAKINRA | 17 | 0.1% | 0 | 10 | 0 |
| CANAKINUMAB | 17 | 0.2% | 0 | 10 | 0 |
| OMEPRAZOLE | 16 | 0.0% | 1 | 15 | 0 |
| BENDAMUSTINE | 15 | 0.1% | 0 | 15 | 0 |
| ESCITALOPRAM OXALATE | 15 | 0.1% | 0 | 15 | 0 |
| OBINUTUZUMAB | 15 | 0.1% | 0 | 15 | 0 |
| ROSIGLITAZONE | 15 | 0.0% | 5 | 11 | 0 |
| SULFAMETHOXAZOLE\TRIMETHOPRIM | 15 | 0.0% | 0 | 15 | 0 |
| ADALIMUMAB | 8 | 0.0% | 3 | 5 | 1 |
| PARICALCITOL | 6 | 0.1% | 6 | 0 | 0 |
| SACUBITRIL\VALSARTAN | 6 | 0.0% | 2 | 0 | 0 |
| ATENOLOL\NIFEDIPINE | 5 | 18.5% | 0 | 0 | 0 |
| AVANDIA | 5 | 0.2% | 1 | 2 | 0 |
| BENFLUOREX | 5 | 10.0% | 0 | 0 | 0 |
| IMATINIB | 5 | 0.0% | 2 | 2 | 0 |
| PARSACLISIB | 5 | 6.8% | 0 | 5 | 0 |