Immune effector cell-associated neurotoxicity syndrome: Which Medications Cause It? (4,516 Reports Across 84 Drugs)
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Immune effector cell-associated neurotoxicity syndrome has been reported as an adverse event with 84 different drugs in the FDA's FAERS database, with 4,516 total reports. 1,123 of these reports resulted in death.The drugs most commonly associated with Immune effector cell-associated neurotoxicity syndrome are AXICABTAGENE CILOLEUCEL, BREXUCABTAGENE AUTOLEUCEL, and CYCLOPHOSPHAMIDE.
4,516
Total Reports
84
Drugs Involved
1,123
Deaths
2,173
Hospitalizations
59.9 yrs
Average Patient Age
42.2% / 57.8%
Female / Male
Which Drugs Cause Immune effector cell-associated neurotoxicity syndrome Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| AXICABTAGENE CILOLEUCEL | 1,821 | 21.2% | 402 | 903 | 284 |
| BREXUCABTAGENE AUTOLEUCEL | 529 | 30.3% | 123 | 291 | 72 |
| CYCLOPHOSPHAMIDE | 468 | 0.4% | 108 | 289 | 86 |
| TISAGENLECLEUCEL | 416 | 9.8% | 127 | 183 | 72 |
| FLUDARABINE | 331 | 1.4% | 77 | 245 | 71 |
| RITUXIMAB | 305 | 0.2% | 84 | 134 | 45 |
| DEXAMETHASONE | 267 | 0.2% | 85 | 143 | 48 |
| CILTACABTAGENE AUTOLEUCEL | 232 | 6.1% | 78 | 126 | 24 |
| DOXORUBICIN | 189 | 0.2% | 43 | 82 | 26 |
| PREDNISONE | 179 | 0.1% | 45 | 75 | 23 |
| IDECABTAGENE VICLEUCEL | 176 | 17.0% | 30 | 72 | 20 |
| VINCRISTINE | 164 | 0.2% | 39 | 77 | 25 |
| TECLISTAMAB-CQYV | 153 | 9.6% | 43 | 67 | 12 |
| TOCILIZUMAB | 146 | 0.2% | 53 | 66 | 26 |
| BLINATUMOMAB | 145 | 1.6% | 25 | 51 | 29 |
| CYTARABINE | 141 | 0.3% | 31 | 68 | 31 |
| LISOCABTAGENE MARALEUCEL | 129 | 17.5% | 22 | 74 | 17 |
| TARLATAMAB-DLLE | 127 | 15.8% | 15 | 51 | 22 |
| ETOPOSIDE | 99 | 0.2% | 19 | 57 | 16 |
| TECLISTAMAB | 99 | 8.1% | 34 | 45 | 7 |
Top 3 Drugs Associated With Immune effector cell-associated neurotoxicity syndrome
1,821 reports
529 reports
468 reports