Infantile spasms: Which Medications Cause It? (531 Reports Across 20 Drugs)
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Infantile spasms has been reported as an adverse event with 20 different drugs in the FDA's FAERS database, with 531 total reports. 12 of these reports resulted in death.The drugs most commonly associated with Infantile spasms are VIGABATRIN, CORTICOTROPIN, and LEVETIRACETAM.
531
Total Reports
20
Drugs Involved
12
Deaths
190
Hospitalizations
1.5 yrs
Average Patient Age
46.2% / 53.8%
Female / Male
Which Drugs Cause Infantile spasms Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| VIGABATRIN | 257 | 2.1% | 6 | 91 | 1 |
| CORTICOTROPIN | 86 | 0.7% | 2 | 30 | 0 |
| LEVETIRACETAM | 70 | 0.1% | 2 | 14 | 2 |
| TOPIRAMATE | 39 | 0.1% | 0 | 11 | 0 |
| VALPROIC ACID | 37 | 0.2% | 1 | 9 | 1 |
| OXCARBAZEPINE | 25 | 0.2% | 0 | 2 | 0 |
| VALPROATE | 22 | 0.1% | 0 | 5 | 0 |
| SABRIL | 15 | 1.9% | 0 | 4 | 0 |
| CARBAMAZEPINE | 14 | 0.1% | 0 | 2 | 0 |
| PALIVIZUMAB | 13 | 0.1% | 0 | 10 | 0 |
| CLOBAZAM | 12 | 0.1% | 1 | 5 | 0 |
| LAMOTRIGINE | 12 | 0.0% | 0 | 1 | 0 |
| EVEROLIMUS | 10 | 0.0% | 0 | 1 | 0 |
| PREDNISOLONE | 10 | 0.0% | 0 | 3 | 0 |
| LACOSAMIDE | 9 | 0.0% | 1 | 2 | 0 |
| PHENOBARBITAL | 9 | 0.1% | 1 | 2 | 0 |
| CLONAZEPAM | 8 | 0.0% | 1 | 2 | 0 |
| CANNABIDIOL | 7 | 0.0% | 0 | 2 | 0 |
| METHOTREXATE | 6 | 0.0% | 0 | 0 | 0 |
| ZONISAMIDE | 6 | 0.1% | 0 | 1 | 0 |