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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Injection site discomfort: Which Medications Cause It? (8,235 Reports Across 199 Drugs)

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Injection site discomfort has been reported as an adverse event with 199 different drugs in the FDA's FAERS database, with 8,235 total reports. 59 of these reports resulted in death.The drugs most commonly associated with Injection site discomfort are ETANERCEPT, DUPILUMAB, and ADALIMUMAB.

8,235
Total Reports
199
Drugs Involved
59
Deaths
578
Hospitalizations
51.4 yrs
Average Patient Age
64.8% / 35.2%
Female / Male

Which Drugs Cause Injection site discomfort Most Often?

Drug Reports % of Drug Reports Deaths Hosp. Life-Threat.
ETANERCEPT 1,095 0.3% 2 36 0
DUPILUMAB 833 0.2% 1 16 0
ADALIMUMAB 493 0.1% 0 37 0
EVOLOCUMAB 480 0.3% 0 2 0
DULAGLUTIDE 368 0.5% 0 5 0
TIRZEPATIDE 317 0.3% 0 2 0
NALTREXONE 225 0.9% 0 10 0
SOMATROPIN 195 0.3% 0 7 0
OCTREOTIDE 194 0.8% 24 113 8
TERIPARATIDE 192 0.3% 0 1 0
GALCANEZUMAB-GNLM 187 0.7% 0 2 0
EXENATIDE 164 0.5% 0 3 0
LEUPROLIDE 164 0.2% 6 22 6
GLATIRAMER 135 0.3% 0 3 0
SECUKINUMAB 130 0.1% 0 10 2
IXEKIZUMAB 126 0.4% 0 1 0
OMALIZUMAB 125 0.2% 2 46 6
INSULIN GLARGINE 105 0.1% 0 5 0
INSULIN LISPRO 95 0.1% 0 1 0
ABALOPARATIDE 94 0.4% 0 1 0

View all 199 drugs →

Top 3 Drugs Associated With Injection site discomfort

1,095 reports
833 reports
493 reports

Related Side Effects

Drug ineffective (1,049,718) Off label use (762,782) Death (660,423) Fatigue (599,248) Nausea (562,301) Diarrhoea (491,550) Pain (471,975) Headache (460,069) Dyspnoea (409,496) Dizziness (352,922)