Injection site necrosis: Which Medications Cause It? (1,162 Reports Across 62 Drugs)
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Injection site necrosis has been reported as an adverse event with 62 different drugs in the FDA's FAERS database, with 1,162 total reports. 17 of these reports resulted in death.The drugs most commonly associated with Injection site necrosis are GLATIRAMER, BUPRENORPHINE, and INTERFERON BETA-1A.
1,162
Total Reports
62
Drugs Involved
17
Deaths
185
Hospitalizations
49.6 yrs
Average Patient Age
68.6% / 31.4%
Female / Male
Which Drugs Cause Injection site necrosis Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| GLATIRAMER | 248 | 0.5% | 0 | 12 | 0 |
| BUPRENORPHINE | 91 | 0.1% | 0 | 8 | 0 |
| INTERFERON BETA-1A | 71 | 0.1% | 1 | 14 | 0 |
| INTERFERON BETA-1B | 68 | 0.6% | 0 | 5 | 1 |
| NALTREXONE | 59 | 0.2% | 0 | 20 | 4 |
| FULVESTRANT | 43 | 0.2% | 1 | 4 | 0 |
| APOMORPHINE | 42 | 0.5% | 0 | 12 | 0 |
| DICLOFENAC | 38 | 0.0% | 2 | 11 | 1 |
| HUMAN IMMUNOGLOBULIN G | 32 | 0.1% | 0 | 4 | 0 |
| DEOXYCHOLIC ACID | 29 | 1.3% | 0 | 4 | 1 |
| LEUPROLIDE | 24 | 0.0% | 1 | 1 | 0 |
| MEDROXYPROGESTERONE | 19 | 0.2% | 0 | 1 | 0 |
| ADALIMUMAB | 15 | 0.0% | 0 | 2 | 0 |
| ENOXAPARIN | 15 | 0.1% | 0 | 5 | 0 |
| TRIAMCINOLONE ACETONIDE | 14 | 0.1% | 0 | 2 | 0 |
| METHOTREXATE | 12 | 0.0% | 0 | 0 | 0 |
| CABOTEGRAVIR | 11 | 0.1% | 0 | 5 | 0 |
| RILPIVIRINE | 11 | 0.2% | 0 | 5 | 0 |
| ARTICAINE\EPINEPHRINE | 10 | 0.6% | 0 | 0 | 0 |
| BUPRENORPHINE\NALOXONE | 10 | 0.1% | 0 | 3 | 0 |