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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Instillation site irritation: Which Medications Cause It? (761 Reports Across 19 Drugs)

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Instillation site irritation has been reported as an adverse event with 19 different drugs in the FDA's FAERS database, with 761 total reports. 1 of these reports resulted in death.The drugs most commonly associated with Instillation site irritation are LIFITEGRAST, CYCLOSPORINE, and LOTILANER.

761
Total Reports
19
Drugs Involved
1
Deaths
7
Hospitalizations
65.7 yrs
Average Patient Age
79.8% / 20.2%
Female / Male

Which Drugs Cause Instillation site irritation Most Often?

Drug Reports % of Drug Reports Deaths Hosp. Life-Threat.
LIFITEGRAST 244 1.8% 0 3 0
CYCLOSPORINE 103 0.2% 0 0 0
LOTILANER 94 5.8% 0 1 0
BRIMONIDINE 76 0.6% 0 0 0
KETOTIFEN 21 0.4% 1 0 0
LOTEPREDNOL ETABONATE 19 1.2% 0 0 0
LATANOPROST 18 0.1% 0 0 0
LATANOPROSTENE BUNOD 15 2.8% 0 0 0
DORZOLAMIDE\TIMOLOL 13 0.3% 0 0 0
NAPHAZOLINE\PHENIRAMINE 12 0.6% 0 0 0
TIMOLOL 12 0.2% 0 0 0
VARENICLINE 10 0.1% 0 0 0
DORZOLAMIDE 8 0.2% 0 0 0
POLYMYXIN B\TRIMETHOPRIM 8 2.3% 0 0 0
HYDROCORTISONE\NEOMYCIN\POLYMYXIN B 6 1.8% 0 0 0
CARBOXYMETHYLCELLULOSE 5 0.2% 0 1 0
DESMOPRESSIN 5 0.1% 0 0 0
OFLOXACIN 5 0.2% 0 0 0
PERFLUOROHEXYLOCTANE 5 0.6% 0 0 0

View all 19 drugs →

Top 3 Drugs Associated With Instillation site irritation

244 reports
103 reports
94 reports

Related Side Effects

Drug ineffective (1,049,718) Off label use (762,782) Death (660,423) Fatigue (599,248) Nausea (562,301) Diarrhoea (491,550) Pain (471,975) Headache (460,069) Dyspnoea (409,496) Dizziness (352,922)