Instillation site pain: Which Medications Cause It? (2,130 Reports Across 34 Drugs)
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Instillation site pain has been reported as an adverse event with 34 different drugs in the FDA's FAERS database, with 2,130 total reports. 1 of these reports resulted in death.The drugs most commonly associated with Instillation site pain are LIFITEGRAST, CYCLOSPORINE, and BRIMONIDINE.
2,130
Total Reports
34
Drugs Involved
1
Deaths
9
Hospitalizations
66.5 yrs
Average Patient Age
82.9% / 17.1%
Female / Male
Which Drugs Cause Instillation site pain Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| LIFITEGRAST | 1,281 | 9.6% | 0 | 5 | 0 |
| CYCLOSPORINE | 121 | 0.2% | 0 | 1 | 0 |
| BRIMONIDINE | 98 | 0.8% | 0 | 0 | 0 |
| RESTASIS | 73 | 6.3% | 0 | 0 | 0 |
| NAPHAZOLINE\PHENIRAMINE | 51 | 2.5% | 0 | 0 | 0 |
| KETOTIFEN | 36 | 0.7% | 0 | 0 | 0 |
| LATANOPROST | 36 | 0.2% | 0 | 0 | 0 |
| CARBOXYMETHYLCELLULOSE\GLYCERIN | 34 | 1.5% | 0 | 0 | 0 |
| LOTEPREDNOL ETABONATE | 33 | 2.0% | 0 | 1 | 0 |
| ALAWAY | 24 | 21.1% | 0 | 0 | 0 |
| LATANOPROSTENE BUNOD | 21 | 3.9% | 0 | 0 | 0 |
| DORZOLAMIDE\TIMOLOL | 17 | 0.4% | 0 | 0 | 0 |
| BIMATOPROST | 16 | 0.1% | 0 | 0 | 0 |
| NETARSUDIL | 16 | 1.3% | 0 | 0 | 0 |
| HYDROCORTISONE\NEOMYCIN\POLYMYXIN B | 15 | 4.5% | 0 | 0 | 0 |
| DORZOLAMIDE | 13 | 0.3% | 0 | 0 | 1 |
| BRIMONIDINE\TIMOLOL | 12 | 0.5% | 0 | 0 | 0 |
| BROMFENAC | 12 | 1.0% | 0 | 0 | 0 |
| TIMOLOL | 12 | 0.2% | 0 | 0 | 0 |
| DESMOPRESSIN | 10 | 0.3% | 0 | 0 | 0 |