International normalised ratio increased: Which Medications Cause It? (13,812 Reports Across 550 Drugs)
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International normalised ratio increased has been reported as an adverse event with 550 different drugs in the FDA's FAERS database, with 13,812 total reports. 1,411 of these reports resulted in death.The drugs most commonly associated with International normalised ratio increased are WARFARIN, RIVAROXABAN, and ACETAMINOPHEN.
13,812
Total Reports
550
Drugs Involved
1,411
Deaths
8,534
Hospitalizations
68.1 yrs
Average Patient Age
48.2% / 51.8%
Female / Male
Which Drugs Cause International normalised ratio increased Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| WARFARIN | 5,622 | 13.8% | 493 | 3,554 | 641 |
| RIVAROXABAN | 863 | 0.7% | 58 | 438 | 68 |
| ACETAMINOPHEN | 533 | 0.4% | 64 | 425 | 93 |
| ASPIRIN | 448 | 0.5% | 66 | 336 | 39 |
| APIXABAN | 317 | 0.2% | 30 | 172 | 33 |
| CLOPIDOGREL BISULFATE | 314 | 0.7% | 64 | 240 | 34 |
| FLUINDIONE | 286 | 13.2% | 45 | 220 | 36 |
| AMIODARONE | 277 | 1.1% | 26 | 211 | 29 |
| FUROSEMIDE | 277 | 0.5% | 61 | 225 | 26 |
| DABIGATRAN ETEXILATE | 223 | 0.6% | 34 | 154 | 29 |
| ENOXAPARIN | 217 | 0.9% | 28 | 148 | 24 |
| TREPROSTINIL | 200 | 0.2% | 19 | 121 | 7 |
| ATORVASTATIN | 198 | 0.3% | 18 | 124 | 13 |
| LEVOFLOXACIN | 191 | 0.5% | 16 | 97 | 25 |
| IBUPROFEN | 162 | 0.2% | 9 | 113 | 31 |
| ACENOCOUMAROL | 143 | 11.5% | 9 | 105 | 9 |
| MACITENTAN | 143 | 0.3% | 36 | 109 | 8 |
| CLARITHROMYCIN | 142 | 0.8% | 3 | 121 | 36 |
| FLUCONAZOLE | 137 | 0.9% | 10 | 103 | 23 |
| PANTOPRAZOLE | 137 | 0.2% | 5 | 115 | 4 |