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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Irritable bowel syndrome: Which Medications Cause It? (15,427 Reports Across 706 Drugs)

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Irritable bowel syndrome has been reported as an adverse event with 706 different drugs in the FDA's FAERS database, with 15,427 total reports. 2,198 of these reports resulted in death.The drugs most commonly associated with Irritable bowel syndrome are METHOTREXATE, ABATACEPT, and ADALIMUMAB.

15,427
Total Reports
706
Drugs Involved
2,198
Deaths
5,387
Hospitalizations
50.7 yrs
Average Patient Age
83.6% / 16.4%
Female / Male

Which Drugs Cause Irritable bowel syndrome Most Often?

Drug Reports % of Drug Reports Deaths Hosp. Life-Threat.
METHOTREXATE 4,155 1.6% 1,682 2,060 1,848
ABATACEPT 4,069 3.5% 1,508 1,980 1,793
ADALIMUMAB 3,915 0.8% 1,605 2,133 1,750
LEFLUNOMIDE 3,897 6.9% 1,531 1,980 1,796
TOCILIZUMAB 3,854 3.9% 1,618 1,937 1,627
CERTOLIZUMAB PEGOL 3,740 3.8% 1,461 1,757 1,583
GOLIMUMAB 3,684 5.3% 1,451 1,770 1,591
ETANERCEPT 3,419 1.0% 1,170 1,552 1,297
RITUXIMAB 3,393 1.9% 1,643 2,106 1,814
ACETAMINOPHEN 3,337 2.4% 1,302 1,664 1,444
OXYCODONE 3,241 1.7% 1,273 1,589 1,343
INFLIXIMAB 3,230 2.3% 1,512 1,864 1,658
HYDROXYCHLOROQUINE 3,222 4.8% 1,446 1,780 1,557
CHLORHEXIDINE 3,200 35.8% 1,249 1,588 1,347
DICLOFENAC 3,177 3.7% 1,710 1,953 1,771
ALENDRONATE 3,136 11.3% 1,553 1,954 1,688
PREDNISONE 3,132 2.0% 1,527 1,915 1,703
SULFASALAZINE 3,117 7.8% 1,478 1,777 1,608
TOFACITINIB 3,097 2.0% 1,376 1,714 1,516
CETIRIZINE 3,038 6.4% 1,508 1,817 1,627

View all 706 drugs →

Top 3 Drugs Associated With Irritable bowel syndrome

4,155 reports
4,069 reports
3,915 reports

Related Side Effects

Drug ineffective (1,049,718) Off label use (762,782) Death (660,423) Fatigue (599,248) Nausea (562,301) Diarrhoea (491,550) Pain (471,975) Headache (460,069) Dyspnoea (409,496) Dizziness (352,922)