Labelled drug-drug interaction issue: Which Medications Cause It? (1,157 Reports Across 171 Drugs)
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Labelled drug-drug interaction issue has been reported as an adverse event with 171 different drugs in the FDA's FAERS database, with 1,157 total reports. 98 of these reports resulted in death.The drugs most commonly associated with Labelled drug-drug interaction issue are ASPIRIN, QUETIAPINE, and BUPROPION\NALTREXONE.
1,157
Total Reports
171
Drugs Involved
98
Deaths
374
Hospitalizations
57.8 yrs
Average Patient Age
54.7% / 45.3%
Female / Male
Which Drugs Cause Labelled drug-drug interaction issue Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| ASPIRIN | 75 | 0.1% | 8 | 20 | 2 |
| QUETIAPINE | 70 | 0.1% | 41 | 21 | 18 |
| BUPROPION\NALTREXONE | 65 | 0.8% | 0 | 8 | 0 |
| POSACONAZOLE | 47 | 0.8% | 0 | 4 | 0 |
| BUPROPION | 42 | 0.1% | 19 | 0 | 4 |
| CLOPIDOGREL BISULFATE | 42 | 0.1% | 4 | 15 | 4 |
| FLUTICASONE FUROATE\UMECLIDINIUM\VILANTEROL TRIFENATATE | 42 | 0.2% | 0 | 1 | 0 |
| RIVAROXABAN | 39 | 0.0% | 3 | 21 | 6 |
| OMEPRAZOLE | 37 | 0.0% | 0 | 16 | 1 |
| TACROLIMUS | 37 | 0.0% | 0 | 12 | 0 |
| PAROXETINE | 35 | 0.2% | 21 | 20 | 18 |
| HYDROMORPHONE | 34 | 0.0% | 14 | 9 | 3 |
| IBUPROFEN | 34 | 0.0% | 21 | 18 | 20 |
| ACETAMINOPHEN | 32 | 0.0% | 5 | 21 | 7 |
| LAMOTRIGINE | 32 | 0.1% | 4 | 17 | 0 |
| OXYCODONE | 32 | 0.0% | 8 | 18 | 10 |
| TRAMADOL | 32 | 0.0% | 10 | 19 | 12 |
| METHOTREXATE | 30 | 0.0% | 5 | 23 | 3 |
| CITALOPRAM HYDROBROMIDE | 29 | 0.1% | 21 | 3 | 0 |
| LORAZEPAM | 28 | 0.1% | 15 | 2 | 2 |